A Sensitive Method to Quantify Senescent Cancer Cells
Title:
A Sensitive Method to Quantify Senescent Cancer Cells
Author:
Cahu, Julie
Personal Author:
Publication Information:
Cambridge, MA MyJoVE Corp 2016
Physical Description:
online resource (558 seconds)
Series:
Medicine
General Note:
Title from resource description page
Abstract:
Whether senescence prevents or promotes tumorigenesis remains controversial. Since chemotherapeutical drugs can induce cancer cells to senesce, studying senescence is essential for proposing new therapies. However, the standard and broadly used β-galactosidase assay presents major drawbacks. We propose here a rapid and sensitive flow cytometry-based assay to quantify senescence.
Reading Level:
For undergraduate, graduate, and professional students
Subject Term:
Electronic Access:
https://www.jove.com/t/50494