Bioprocessing is a method that uses living organisms to produce a desired target product. Often, bioprocessing refers to the use of bioreactors to produce protein products from genetically engineered organisms. This field is responsible for the large-scale manufacture of biotherapeutics; drugs that have become essential to improving the quality of life for many with complex diseases like cancer, autoimmune diseases and HIV/AIDS. This video will introduce the engineering approach to designing a targeted protein-production system. The prominent methods in the field, as well as some key challenges, and applications of the technology are also considered.