Intro -- Box 1. A tale of two cities: social determinants and vector-borne disease in Brownsville, Texas, United States of America, and Matamoros, Tamaulipas, Mexico -- Box 2. Deforestation and urbanization in Guangdong province, China -- Box 3. Malaria elimination in the Eastern Mediterranean Region -- Box 4. Public disapproval of a public health intervention: aerial application of insecticide to control Zika virus disease, Puerto Rico, 2016 -- Box 5. Mass drug administration targeting lymphatic filariasis in Assam, India -- Box 6. Ethical controversy surrounding the use of CYD-TDV dengue vaccine -- Box 7. Better practices for safer water storage: compulsory vector control measures and targeted surveillance in India -- Box 8. The eye in the sky: use of drone technology for disease surveillance in Singapore -- Box 9. Use of human movement data to show spread of Zika virus in Singapore -- Box 10. The World Mosquito Programme: informed consent in field trials -- Box 11. Malaria human challenge study in Nairobi, Kenya -- Box 12. Conflicts over the release of genetically modified mosquitoes in Burkina Faso -- Acknowledgements -- 1. Introduction -- 2. Background -- 2.1 Key facts about vector-borne diseases -- 2.2 Social determinants of vector-borne diseases -- 2.3 Environmental determinants of vector-borne diseases -- 3. Relevant ethical issues and values -- 4. Addressing social and environmental determinants -- 5. General ethical considerations for public health interventions -- 6. Vector control methods -- 7. Vaccine campaigns and mass drug administration -- 8. Screening and surveillance -- 9. Research -- 10. Community engagement -- References.