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DNA Repair and Human Disease
Title:
DNA Repair and Human Disease
Author:
Balajee, Adayabalam S. author.
ISBN:
9780387368023
Physical Description:
XII, 150 p. online resource.
Series:
Medical Intelligence Unit
Contents:
Human Premature Aging Disorders and Dysfunction of DNA Repair -- DNA Repair Aspects for RecQ Helicase Disorders -- Trichothiodystrophy -- Roles of the BRCA1 and BRCA2 Breast Cancer Susceptibility Proteins in DNA Repair -- Radiosensitivity of Cells Derived from Down Syndrome Patients -- The Fanconi Anemia/BRCA Pathway -- Is Ataxia Telangiectasia a Result of Impaired Coordination between DNA Repair and Cell Cycle Checkpoint Regulators? -- Mechanisms of DNA Damage and Repair in Alzheimer Disease -- Orchestration of Telomeres and DNA Repair Factors in Mammalian Cells -- Defective Solar Protection in Xeroderma Pigmentosum and Cockayne Syndrome Patients.
Abstract:
DNA Repair and Human Disease highlights the molecular complexities of a few well-known human hereditary disorders that arise due to perturbations in the fidelity of diverse DNA repair machineries.
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