Split-and-pool Synthesis and Characterization of Peptide Tertiary Amide Library
Title:
Split-and-pool Synthesis and Characterization of Peptide Tertiary Amide Library
Author:
Gao, Yu
Personal Author:
Publication Information:
Cambridge, MA MyJoVE Corp 2016
Physical Description:
online resource (817 seconds)
Series:
Chemistry
General Note:
Title from resource description page
Abstract:
Peptide tertiary amides (PTAs) are a superfamily of peptidomimetics that include but are not limited to peptides, peptoids and N-methylated peptides. Here we describe a synthetic method which combines both split-and-pool and sub-monomer strategies to synthesize a one-bead one-compound library of PTAs.
Reading Level:
For undergraduate, graduate, and professional students
Subject Term:
Electronic Access:
https://www.jove.com/t/51299