Contents -- Preface -- 1. Introduction: Nanobiotechnology and Bionanotechnology -- 1.1 Classical Biotechnology: Industrial Production Using Biological Systems -- 1.2 Modern Biotechnology: From Industrial Processes to Novel Therapeutics -- 1.3 Modern Biotechnology: Immunological, Enzymatic, and Nucleic Acids-Based Technology -- 1.4 The Interface Between Nanotechnological and Biotechnology: Bionanotechnology -- 1.5 Supramolecular (Bio)Chemistry: The Theoretical Basis for Self-Assembly -- 1.6 The Next Steps for Self-Association at the Nano-Scale -- 1.7 Biology in Nanotechnology and Nano-Sciences in Biotechnology -- 1.8 The Combination of Bionanotechnology and Nanobiotechnology -- 1.9 Nanobionics and Bio-Inspired Nanotechnology -- 2. A Brief Introduction to Nanotechnology -- 2.1 The Emergence of Nanotechnology: "There's Plenty of Room at the Bottom" -- 2.2 Coining the Term "Nanotechnology" and Emergence of the Nanotechnology Concept -- 2.3 Manipulating Molecules: The Scanning Probe Microscopes -- 2.4 Carbon Fullerene: A New Form of Carbon -- 2.5 Carbon Nanotubes: Key Building Blocks for Future Nanotechnological Applications -- 2.6 Non-Carbon Nanotubes and Fullerene-Like Material: The Inorganic Nanomaterials -- 2.7 Quantum Dots and Other Nano-Particles -- 2.8 Nanowires, Nanorods, and Other Nanomaterials -- 2.9 Magnetic Nanoparticles -- 3. Natural Biological Assembly at the Nano-Scale -- 3.1 The Process of Self-Assembly and Self-Organization in Biology. -- 3.2 Organization of Bacterial S-Layers -- 3.3 Self-Organization of Viruses -- 3.4 Self-Organization of Phospholipids Membranes -- 3.5 Fibrillar Cytoskeleton Assemblies -- 3.6 Nucleic Acids: The Genetic Information Media and a Template for Nanotechnological Applications -- 3.7 Oligosaccharides and Polysaccharides: Another Class of Biological Polymers.

3.8 Amyloid Fibrils as Self-Assembled Nano-Scale Bio-Assemblies -- 3.9 Silk: Natural Fibrillar Supramolecular Protein Assembly -- 3.10 Ribosome: The Protein Assembly Line Instrument -- 3.11 Other Complex Machines in the Genetic Code Expression -- 3.12 Protein Quality-Control Machinery: The Proteosome -- 3.13 Biological Nano-Motors: Kinesin and Dynein -- 3.14 Other Nano-Motors: Flagella and Cilia -- 3.15 Ion Channels: Nano-Pores of High Specificity -- 4. Nanometric Biological Assemblies: Molecular and Chemical Basis for Interaction -- 4.1 Emergence of Biological Activity Through Self-Assembly -- 4.2 Molecular Recognition and Chemical Affinity -- 4.3 Affinity and Specificity of Biological Interactions -- 4.4 The Relation Between Thermodynamics and Kinetics of Dissociation -- 4.5 The Chemical Basis for Molecular Recognition and Specific Binding -- 4.6 The Formation Specific Complexes by an Increase in Entropy -- 5. Molecular Recognition and the Formation of Biological Structures -- 5.1 Antibodies as the Molecular Sensors of Recognition -- 5.2 Selection of Antibodies and Equivalent Systems in the Test Tube -- 5.3 Recognition Between Nucleic Acids by Proteins -- 5.4 Interaction Between Receptors and Ligands -- 5.5 Molecular Recognition Between Nucleic Acids -- 6. Self-Assembly of Biological and Bio-Inspired Nano-Materials -- 6.1 Formation of DNA-Based Materials -- 6.2 Peptide-Based Nanomaterials -- 6.3 The First Peptide Nanotubes -- 6.4 Amphiphile and Surfactant-Like Peptide Building-Blocks -- 6.5 Charge Complementary as a Driven Force for Self-Assembly -- 6.6 Conjugation of Peptides for Self-Assembly -- 6.7 Aromatic Interactions for the Formation of Nanostructures -- 6.8 The Formation of Aromatic Dipeptide Nanotubes (ADNT) -- 6.9 The Formation of Spherical Nanostructures by Short Peptides -- 6.10 Peptide Nucleic Acid (PNA).

7. Application of Biological Assemblies in Nanotechnology -- 7.1 The Use of S-Layer for Nanolithography -- 7.2 The Use of DNA for Fabrication of Conductive Nanowires -- 7.3 Amyloid Fibrils as Templates for Nanowires Fabrication -- 7.4 Metallization of Actin Filaments by Chemical Modification -- 7.5 The Use of Aromatic Peptide Nanotubes -- 7.6 Bacteriophages as Novel Biomaterials -- 7.7 The Use of Peptide Template for Biomineralization -- 7.8 Production of Inorganic Composite Nanomaterial -- 7.9 The Utilization of Biomineralization in Nanotechnology -- 8. Medical and Other Applications of Bionanotechnology -- 8.1 The Use of Drug Nanocrystals for Improved Application -- 8.2 The Use of Nano-Containers for Drug Delivery -- 8.3 The Use of Inorganic Nanowires for Biological Detection -- 8.4 The Use of Soft Lithography for Biotechnology -- 8.5 Contrast Agents by Nanomagnetic Materials -- 8.6 Nanoagriculture -- 8.7 Water Technology and Nanotechnology -- 8.8 Nanocosmetics -- 8.9 Solar Energy Applications -- 9. Future Prospects for Nanobiotechnology and Bionanotechnology -- 9.1 The Marriage of Molecular Biology and Nanotechnology -- 9.2 The Engineering of Modified Biological Systems for the Assembly of Nanostructures -- 9.3 Nanotechnology and Tissue Engineering -- 9.4 Engineering of the Brain Tissue -- 9.5 Making Artificial Biological Inorganic Composites -- 9.6 Nanobio Machines and Nanorobots -- 10. Concluding Remarks: The Prospects and Dangers of the Nanobiological Revolution -- Appendix A There's Plenty of Room at the Bottom: An Invitation to Enter a New Field of Physics - by Richard P. Feynman -- There's Plenty of Room at the Bottom: An Invitation to Enter a New Field of Physics -- How do we write small? -- Information on a small scale -- Better electron microscopes -- The marvelous biological system -- Miniaturizing the computer.

Miniaturization by evaporation -- Problems of lubrication -- A hundred tiny hands -- Rearranging the atoms -- Atoms in a small world -- High school competition -- Appendix B List of Bionanotechnological and Nanobiotechnological Companies -- Appendix C Glossary -- Bibliography -- Index.