Single Molecule Analysis of Laser Localized Psoralen Adducts
Title:
Single Molecule Analysis of Laser Localized Psoralen Adducts
Author:
Huang, Jing
Personal Author:
Publication Information:
Cambridge, MA MyJoVE Corp 2016
Physical Description:
online resource (706 seconds)
Series:
Genetics
General Note:
Title from resource description page
Abstract:
Lasers are frequently used in studies of the cellular response to DNA damage. However, they generate lesions whose spacing, frequency, and collisions with replication forks are rarely characterized. Here, we describe an approach that enables the determination of these parameters with laser localized interstrand crosslinks.
Reading Level:
For undergraduate, graduate, and professional students
Subject Term:
Electronic Access:
https://www.jove.com/t/55541