Preface -- 1 Basic design considerations -- 2 Distributions and confidence intervals -- 3 Comparing two independent groups for binary data -- 4 Comparing two independent groups for ordered categorical data -- 5 Comparing two independent groups for continuous data -- 6 Cluster designs, repeated measures data and more than two groups -- 7 Comparing paired groups for binary, ordered categorical and continuous outcomes -- 8 Comparing survival curves -- 9 Equivalence -- 10 Confidence intervals -- 11 Post-marketing surveillance -- 12 The correlation coefficient -- 13 Reference intervals and receiver operating curves -- 14 Observer agreement studies -- 15 Dose finding studies -- 16 Phase II trials -- 17 Sample size software S SS -- Cumulative references -- Author index -- Subject index.