Front Matter -- Contents -- Summary -- Introduction -- 1 Biomarker and Biosignature Principles -- 2 Potential Tools for Biomarker and Biosignature Development -- 3 Psychiatric and Drug Addiction Disorders -- 4 Neurological and Eye Diseases -- Appendixes -- A References -- B Public Workshop on Neuroscience Biomarkers and Biosignatures: Converging Technologies, Emerging Partnerships -- C Workshop Attendees -- D Biographical Sketches of Invited Speakers, Committee Members, and Staff.