Acknowledgments -- Glossary -- Contents -- Summary -- Introduction -- 1 Pain in Research Animals: General Principles and Considerations -- 2 Mechanisms of Pain -- 3 Recognition and Assessment of Pain -- 4 Effective Pain Management -- 5 Humane Endpoints for Animals in Pain -- Appendixes -- Appendix A: Models of Pain -- Appendix B: US Regulations and Guidelines Regarding Recognition and Alleviation of Pain in Laboratory Animals -- Appendix C: About the Authors -- Index.