Clinical Hematology -- CONTRIBUTORS -- PREFACE -- ACKNOWLEDGMENTS -- CONTENTS -- PART I Laboratory Hematology -- Examination of the Blood and Bone Marrow -- Clinical Flow Cytometry -- Cytogenetics -- Molecular Diagnosis in Hematology -- PART II The Normal Hematologic System -- SECTION 1: Hematopoiesis -- Origin and Development of Blood Cells -- SECTION 2: The Erythrocyte -- The Birth, Life, and Death of Red Blood Cells: Erythropoiesis, The Mature Red Blood Cell, and Cell Destruction -- SECTION 3: Granulocytes and Monocytes -- Neutrophilic Leukocytes -- The Human Eosinophil -- Mast Cells and Basophils: Ontogeny, Characteristics, and Functional Diversity -- Monocytes, Macrophages, and Dendritic Cells -- SECTION 4:The Lymphocytes -- Lymphocytes and Lymphatic Organs -- B Lymphocytes -- T Lymphocytes and Natural Killer Cells -- Effector Mechanisms In Immunity -- SECTION 5: HEMOSTASIS -- Megakaryocytes -- Platelet Structure and Function in Hemostasis and Thrombosis -- Platelet Function in Hemostasis and Thrombosis -- Blood Coagulation And Fibrinolysis -- Endothelium: Angiogenesis and the Regulation of Hemostasis -- PART III Transfusion Medicine -- Red Cell, Platelet, and White Cell Antigens -- Transfusion Medicine -- PART IV Disorders of Red Cells -- SECTION 1: Introduction -- Anemia:General Considerations -- SECTION 2: Disorders of Iron Metabolismand Heme Synthesis -- Iron Deficiency and Related Disorders -- Sideroblastic Anemias -- Hemochromatosis -- Porphyrias -- SECTION 3: Hemolytic Anemia -- Hereditary Spherocytosis, Hereditary Elliptocytosis, And Other Disorders Associated With Abnormalities Of The Erythrocyte Membrane -- Hereditary Hemolytic Anemias Due to Red Blood Cell Enzyme Disorders -- Autoimmune Hemolytic Anemia -- Hemolytic Disease of the Fetus and Newborn -- Paroxysmal Nocturnal Hemoglobinuria -- Acquired Nonimmune Hemolytic Disorders.

SECTION 4: Hereditary Disorders ofHemoglobin Structure and Synthesis -- Sickle Cell Anemia and Other Sickling Syndromes -- Thalassemias and Related Disorders: Quantitative Disorders of Hemoglobin Synthesis -- Hemoglobins with Altered Oxygen Affinity, Unstable Hemoglobins, M-Hemoglobins, and Dyshemoglobinemias -- SECTION 5: Other Red Cell Disorders -- Megaloblastic Anemias:Disorders Of Impaired Dna Synthesis -- Inherited Aplastic Anemia Syndromes -- Acquired Aplastic Anemia -- Red Cell Aplasia: Acquired And Congenital Disorders -- Congenital Dyserythropoietic Anemias -- Anemias Secondary to Chronic Disease and Systemic Disorders -- Anemias During Pregnancy and the Postpartum Period -- Anemias Unique to the Fetus and Neonate -- Erythrocytosis -- PART V Disorders of Hemostasis and Coagulation -- SECTION 1: Introduction -- Diagnostic Approach to the Bleeding Disorders -- SECTION 2: Thrombocytopenia -- Thrombocytopenia: Pathophysiology and Classification -- Thrombocytopenia Caused by Immunologic Platelet Destruction -- Thrombotic Thrombocytopenic Purpura, Hemolytic-Uremic Syndrome, and Related Disorders -- Miscellaneous Causes of Thrombocytopenia -- Bleeding Disorders Caused by Vascular Abnormalities -- Thrombocytosis And Essential Thrombocythemia -- Qualitative Disorders of Platelet Function -- SECTION 4: Coagulation Disorders -- Inherited Coagulation Disorders -- Acquired Coagulation Disorders -- SECTION 5: Thrombosis -- Thrombosis And Antithrombotic Therapy -- PART VI Benign Disorders of Leukocytes, the Spleen, and/or Immunoglobins -- Diagnostic Approach to Malignant and Nonmalignant Disorders of the Phagocytic and Immune Systems -- Neutropenia -- Qualitative Disorders of Leukocytes -- Lysosomal Abnormalities of the Monocyte-Macrophage System: Gaucher and Niemann-Pick Diseases -- Langerhans Cell Histiocytosis.

Pathology of Langerhans Cell Histiocytosis and Other Histiocytic Proliferations -- Infectious Mononucleosis and Other Epstein-Barr Virus-Related Disorders -- Primary Immunodeficiency Syndromes -- Acquired Immunodeficiency Syndrome -- Disorders of the Spleen -- Tumors of the Spleen -- PART VII Hematologic Malignancies -- SECTION 1: General Aspects -- Hematopoietic Neoplasms: Principles of Pathologic Diagnosis -- Principles and Pharmacology of Chemotherapy -- SUPPORTIVE CARE IN HEMATOLOGIC MALIGNANCIES -- Immunotherapy -- Gene Therapy For Hematologic Disorders -- SECTION 2: The Acute Leukemias -- Molecular Genetics Of Acute Leukemia -- Diagnosis and Classification of the Acute Leukemias and Myelodysplastic Syndromes -- ACUTE LYMPHOBLASTIC LEUKEMIA IN ADULTS -- Acute Myeloid Leukemia in Adults -- ACUTE LYMPHOBLASTIC LEUKEMIA IN CHILDREN -- ACUTE MYELOGENOUS LEUKEMIA IN CHILDREN -- Acute Promyelocytic Leukemia -- THE MYELODYSPLASTIC SYNDROMES -- SECTION 3: Myeloproliferative Disorders -- Pathology of The Myeloproliferative Neoplasms -- Chronic Myeloid Leukemia -- Polycythemia Vera -- MYELOFIBROSIS -- Eosinophilic Neoplasms and Hypereosinophilic Syndrome -- Systemic Mastocytosis -- SECTION 4: Lymphoproliferative Disorders -- Diagnosis and Classification of Lymphomas -- Molecular Genetic Aspects of Non-Hodgkin Lymphomas -- Non-Hodgkin Lymphoma In Adults -- Non-Hodgkin Lymphoma in Children -- Chronic Lymphocytic Leukemia -- Hairy Cell Leukemia -- Cutaneous T-Cell Lymphoma: Mycosis Fungoides and Sézary Syndrome -- Hodgkin Lymphoma in Adults -- HODGKIN LYMPHOMA IN CHILDREN -- SECTION 5 PLASMA CELL DYSCRASIAS -- Practical Approach to Evaluation of Monoclonal Gammopathies -- Molecular Genetic Aspects of Plasma Cell Disorders -- Monoclonal Gammopathies Of Undetermined Significance And Smoldering Multiple Myeloma -- Multiple Myeloma.

Immunoglobulin Light-Chain Amyloidosis (Primary Amyloidosis) -- WaldenstrÖm Macroglobulinemia -- Poems Syndrome, Cryoglobulinemia, and Heavy-Chain Disease -- PART VIII Transplantation -- Hematopoietic Cell Transplantation -- Hematopoietic Stem Cell Transplantation for Nonmalignant Disorders -- ALLOGENEIC HEMATOPOIETIC STEM CELL TRANSPLANTATION (HCT) FOR HEMATOLOGIC MALIGNANCIES -- Graft-Versus-Host Disease And Graft-VersusTumor Response -- Late Effects After Transplantation -- Index.