COVER -- COPYRIGHT -- Editors -- DEDICATION -- PREFACE -- CONTENTS -- SECTION I - RECOGNITION: INNATE AND ADAPTIVE IMMUNITY -- 1 - INNATE IMMUNITY LINKAGES TO ADAPTIVE RESPONSES -- 2 - ARCHITECTURE OF THE IMMUNE SYSTEM -- 3 - MAJOR HISTOCOMPATIBILITY GENE COMPLEX STRUCTURE AND FUNCTION -- 4 - T-CELL ANTIGEN RECEPTORS -- 5 - T-CELL BIOLOGY AND THE THYMUS -- 6 - ANTIGEN PROCESSING AND PRESENTATION -- 7 - IMMUNOGENICITY AND ANTIGENICITY -- 8 - LYMPHOCYTE SIGNALING -- 9 - T-LYMPHOCYTE ACTIVATION, COSTIMULATION, AND TOLERANCE: SIGNALS,MECHANISMS, AND CLINICAL APPLICATIONS -- 10 - CYTOKINES AND TYPE 1 IMMUNITY -- 11 - CYTOKINE REGULATION OF TYPE 2 IMMUNITY -- 12 - APOPTOSIS AND THE IMMUNE RESPONSE -- 13 - ANTIBODIES AND THEIR RECEPTORS -- 14 - BIOLOGY OF B CELLS -- 15 - ADHESION MOLECULES -- 16 - CHEMOKINES AND CHEMOKINE RECEPTORS -- 17 - HEMATOPOIETIC CYTOKINES -- SECTION II - EFFECTOR MECHANISMS: INNATE AND ADAPTIVE -- 18 - T-LYMPHOCYTE EFFECTOR ACTIVITY -- 19 - NATURAL KILLER CELLS -- 20 - NEUTROPHILS -- 21 - MONOCYTES AND MACROPHAGES -- 22 - EOSINOPHILS -- 23 - BASOPHILS -- 24 - BIOLOGY OF THE MAST CELL -- 25 - IMMUNE COMPLEXES -- 26 - COMPLEMENT SYSTEM -- 27 - ARACHIDONIC ACID PATHWAYS -- SECTION III - PRIMARY IMMUNODEFICIENCIES -- 28 - PRIMARY IMMUNODEFICIENCIES OF LYMPHOCYTES -- 29 - PHAGOCYTE DISORDERS -- 30 - COMPLEMENT IN DISEASE: INHERITED AND ACQUIRED COMPLEMENTDEFICIENCIES -- 31 - LYMPHOCYTIC LYMPHOMAS AND HODGKIN'S DISEASE -- SECTION IV - PROLIFERATION DISORDERS OF IMMUNOLOGIC CELLS -- 32 - MULTIPLE MYELOMA -- 33 - MACROGLOBULINEMIA -- 34 - AMYLOIDOSIS -- 35 - EOSINOPHILIA -- 36 - MASTOCYTOSIS -- SECTION V - SYSTEMIC DISEASES -- 37 - RHEUMATOID ARTHRITIS -- 38 - JUVENILE RHEUMATOID ARTHRITIS -- 39 - SYSTEMIC LUPUS ERYTHEMATOSUS -- 40 - SJÖGREN'S SYNDROME -- 41 - SYSTEMIC SCLEROSIS (SCLERODERMA).

42 - IDIOPATHIC INFLAMMATORY MYOPATHIES: DERMATOMYOSITIS,POLYMYOSITIS, AND RELATED DISORDERS -- 43 - THE SPONDYLOARTHROPATHIES -- 44 - RHEUMATIC FEVER AND OTHER CARDIOVASCULAR DISEASE -- 45 - VASCULITIS -- 46 - ANTIPHOSPHOLIPID SYNDROME -- 47 - SARCOIDOSIS -- SECTION VI - ORGAN-SPECIFIC DISEASES -- 48 - DIABETES MELLITUS -- 49 - AUTOIMMUNE THYROID DISEASE, ADDISON DISEASE, AND AUTOIMMUNE POLYGLANDULAR SYNDROMES -- 50 - IMMUNOLOGIC RENAL DISEASE -- 51 - MYASTHENIA GRAVIS -- 52 - AUTOIMMUNE BLISTERING MUCOCUTANEOUS DISEASES -- 53 - IMMUNE FUNCTION IN OCULAR INFLAMMATORY DISEASE -- 54 - AUTOIMMUNE HEPATOBILIARY DISEASES -- 55 - IMMUNOLOGIC DISEASES OF THE GASTROINTESTINAL TRACT -- 56 - MULTIPLE SCLEROSIS -- 57 - AUTOIMMUNE HEMOLYTIC ANEMIA -- 58 - IMMUNE THROMBOCYTOPENIA -- 59 - BLOOD GROUPS, IMMUNOLOGIC HAZARDS OF TRANSFUSION, ANDHEMOLYTIC DISEASE OF THE NEWBORN -- 60 - IMMUNOLOGIC ASPECTS OF FERTILITY AND INFERTILITY -- SECTION VII - ALLERGIC DISEASES -- 61 - ALLERGENS -- 62 - GENETICS OF ALLERGIC DISEASE -- 63 - ALLERGIC DISEASES -- 64 - ANAPHYLACTIC SYNDROME -- 65 - ASTHMA -- 66 - URTICARIA AND ANGIOEDEMA: PATHOGENESIS, ASSESSMENT, ANDTREATMENT -- 67 - ATOPIC DERMATITIS -- 68 - ALLERGIC REACTIONS TO FOODS -- 69 - INSECT VENOM ALLERGY -- 70 - IMMUNOLOGIC LUNG DISEASE -- 71 - ALLERGIC CONTACT DERMATITIS -- 72 - ALLERGIC REACTIONS TO DRUGS -- 73 - NATURAL RUBBER LATEX ALLERGY -- SECTION VIII - EVASION, ACTIVATION AND INEFFECTIVE IMMUNITY -- 74 - HUMAN IMMUNODEFICIENCY VIRUS INFECTION -- 75 - EPSTEIN-BARR VIRUS -- 76 - TUBERCULOSIS AND LEPROSY -- 77 - CRYOPATHIES: CRYOGLOBULINS AND CRYOFIBRINOGENEMIA -- 78 - VIRUSES -- 79 - LYME DISEASE -- 80 - PARASITIC DISEASES -- 81 - THE IMMUNOCOMPROMISED HOST -- 82 - AGING AND THE IMMUNE SYSTEM -- SECTION IX - TRANSPLANTATION -- 83 - HEMATOPOIETIC STEM CELL TRANSPLANTATION.

84 - TISSUE AND SOLID ORGAN ALLOGRAFT REJECTION -- 85 - IMMUNOLOGY OF XENOTRANSPLANTATION -- SECTION X - THERAPEUTIC IMMUNOLOGY -- 86 - CALCINEURIN AS A THERAPEUTIC TARGET -- 87 - T-CELL ANTIGEN AND COSTIMULATORY RECEPTORS AS THERAPEUTIC TARGETS -- 88 - CYTOKINES AND CANCER IMMUNOTHERAPY -- 89 - ANTI-TNF-α THERAPHY IN RHEUMATOID ARTHRITIS AND OTHER DISEASES -- 90 - The Use of Intravenous Immunoglobulin -- 91 - MONOCLONAL ANTIBODY THERAPY -- 92 - DRUGS THAT MODULATE THE IMMUNE RESPONSE -- 93 - NEW APPROACHES TO VACCINE DEVELOPMENT -- Appendix A - METHODS -- Appendix B - GLOSSARY -- INDEX -- COLOR FIGURES.