Chronic Constriction of the Sciatic Nerve and Pain Hypersensitivity Testing in Rats
Title:
Chronic Constriction of the Sciatic Nerve and Pain Hypersensitivity Testing in Rats
Author:
Austin, Paul J.
Personal Author:
Publication Information:
Cambridge, MA MyJoVE Corp 2016
Physical Description:
online resource (503 seconds)
Series:
Medicine
General Note:
Title from resource description page
Abstract:
Due to the simplicity of surgery and the robust behavioural outcome, chronic constriction of the sciatic nerve is one of the pre-eminent animal models of neuropathic pain. Within 24 hrs following surgery, pain hypersensitivity is established and can be quantitatively measured using a von Frey aesthesiometer (mechanical test) and plantar analgesia meter (thermal test).
Reading Level:
For undergraduate, graduate, and professional students
Subject Term:
Electronic Access:
https://www.jove.com/t/3393