Epidemiology and prevention of bladder cancer -- Early diagnosis and screening -- Non-invasive diagnosis -- Molecular pathology of tumour progression and metastasis -- Staging: Past, present and future -- Magnetic resonance imaging -- Prognostic factors -- Surgical management -- Transurethral resection in patients with muscle-infiltrating bladder cancer -- Nodal involvement -- Pre-operative and definitive radiation therapy -- Neo-adjuvant and adjuvant chemotherapy — true and false -- Oncological rationale for function-sparing surgery -- Combination therapy and function-sparing surgery for muscle-invasive bladder cancer -- Chemotherapy of metastatic transitional cell cancer -- Invasive transitional cell cancer in the elderly -- Quality of life -- Urethra involvement and bladder cancer -- Lower urinary tract reconstruction -- Salvage cystectomy.