Coagulation testing is the basis for the diagnosis of bleeding and thrombotic disorders, as well as the mainstay of anti-coagulant monitoring and management. This handbook will provide practical information and guidance on the topics relevant to directing a coagulation laboratory and be of interest to pathologists, clinical laboratory scientists, residents, fellows, as well as coagulation laboratory supervisors, technologists and technicians. Sterling T. Bennett, M.D., M.S., is the Medical Director, Intermountain Healthcare Central Laboratory, and Volunteer Adjunct Associate Professor of Pathology, University of Utah Health Sciences Center, Salt Lake City, Utah. Christopher M. Lehman, M.D., is an Associate Professor of Pathology, University of Utah Health Sciences Center and the Assistant Director of Hospital Clinical Laboratories, ARUP, Inc., Salt Lake City, Utah. George M. Rodgers, M.D., Ph.D., is a Professor of Medicine and Pathology, Division of Hematology, University of Utah Health Sciences Center and the Medical Director of the Coagulation Laboratory, ARUP Laboratories, Salt Lake City, Utah. .