Physiology and Pathophysiology -- Neuroregulation of Appetite -- Gut Peptides -- Endocannabinoids and Energy Homeostasis -- Obesity and Adipokines -- Free Fatty Acids, Insulin Resistance, and Ectopic Fat -- Critical Importance of the Perinatal Period in the Development of Obesity -- Measurement of Body Composition in Obesity -- Energy Expenditure in Obesity -- Clinical Management -- Socioeconomics of Obesity -- Assessment of the Obese Patient -- Polycystic Ovary Syndrome -- Weight Management in Diabetes Prevention -- Reductions in Dietary Energy Density as a Weight Management Strategy -- Glycemic Index, Obesity, and Diabetes -- Low-Carbohydrate Diets -- Physical Activity and Obesity -- Motivational Interviewing in Medical Settings -- Weight-Loss Drugs -- Surgical Approaches and Outcomes -- Managing Micronutrient Deficiencies in the Bariatric Surgical Patient -- Lessons Learned From the National Weight Control Registry -- Pediatric Obesity.