BIOTECHNOLOGY: NEW IDEAS, NEW DEVELOPMENTS -- A TEXTBOOK OF MODERN TECHNOLOGY -- BIOTECHNOLOGY IN AGRICULTURE, INDUSTRY AND MEDICINE -- BIOTECHNOLOGY: NEW IDEAS, NEW DEVELOPMENTS -- Library of Congress Cataloging-in-Publication Data -- CONTENTS -- PREFACE -- CHAPTER 1. INTRODUCTION TO BIOTECHNOLOGY -- ABSTRACT -- INTRODUCTION -- HISTORY OF BIOTECHNOLOGY -- HOW BIOTECHNOLOGY WORKS? -- BIOTECHNOLOGY - AN INTERDISCIPLINARY SCIENCE -- APPLICATIONS OF BIOTECHNOLOGY -- [A] Applications in Food Processing and Food Safety -- [B] Applications in Agricultural Sector (Green Biotechnology) -- [C] Applications in Medical Science (Red Biotechnology) -- [D] Applications in Industry (White Biotechnology) -- [E] Applications in Environmental Management -- CONCERNS -- (A) Environmental Concerns -- (B) Health Concerns -- (C) Ethical Debate on Patenting Life -- FUTURE PROSPECTS OF BIOTECHNOLOGY -- REFERENCES -- CHAPTER 2. MARKER ASSISTED SELECTION -- ABSTRACT -- INTRODUCTION -- GENETIC IMPROVEMENT OF PLANTS -- GENETIC MARKERS -- ADVANTAGES OF DNA MARKERS -- MARKER ASSISTED SELECTION -- REQUIREMENTS FOR MAS -- MARKER ASSISTED BREEDING METHODS -- WHEN TO USE MAS? -- QUANTITATIVE TRAIT LOCI (QTL) AND MAS -- APPLICATIONS OF MAS -- WEAKNESS/SHORTCOMING OF MAS -- COST ANALYSIS OF MAS -- MAS AND INTELLECTUAL RIGHTS -- CONCLUSION -- REFERENCES -- CHAPTER 3. METABOLOMICS - THE TECHNOLOGY OF THE FUTURE -- ABSTRACT -- INTRODUCTION -- DEVELOPMENT OF METABOLOMICS -- METABOLOME -- COMPARISON WITH TRANSCRIPTOMICS AND PROTEOMICS -- METABOLOME ANALYSIS -- APPLICATIONS OF METABOLOMICS -- [A] Environmental and Eco-Metabolomics -- Ecophysiology -- Ecotoxicogenomics -- [B] Metabolomics and Crop Improvement -- Future of Metabolomics in Crop Improvement -- [C] Metabolomics and Human Health -- [D] Metabolomics and Cancer -- [E] Metabolomics in Drug Development.

BIOINFORMATICS AND METABOLOMICS -- CONCLUSION -- REFERENCES -- CHAPTER 4. PROTEOMICS: PRINCIPLES, CHALLENGES AND APPLICATIONS -- ABSTRACT -- INTRODUCTION -- THE NEED FOR PROTEOMIC ANALYSIS -- HISTORICAL DEVELOPMENT -- ADVANTAGES OF PROTEOMIC STUDIES -- TECHNIQUES EMPLOYED TO STUDY PROTEINS -- APPLICATIONS OF PROTEOMICS -- [A] Application in Environmental Sciences -- [B] Proteomics in Disease Diagnostics and Drug Discovery -- Proteomics and Biomarkers -- Proteomics in Cancer Research -- [C] Proteomics in Crop Improvement -- [D] Proteomics in Food Science and Technology -- BIOINFORMATICS AND PROTEOMICS -- PROTEOMICS DATABASES -- FUTURE PROSPECTS -- REFERENCES -- CHAPTER 5. THE AGE OF POLYMER THERAPEUTICS -- ABSTRACT -- INTRODUCTION -- CONVENTIONAL DRUG DELIVERY -- TARGETED DRUG DELIVERY -- POLYMERS IN DRUG DELIVERY -- [A] Polymeric Drugs -- [B] Polymer-Drug Conjugates -- [C] Polymer-Protein Conjugates -- [D] Polymeric Micelles -- [E] Multi-Component Polyplexes -- CONCLUSION -- REFERENCES -- CHAPTER 6. NANOMEDICINE: THE NEXT GENERATION MEDICINE -- ABSTRACT -- INTRODUCTION -- HISTORY OF NANOTECHNOLOGY -- NANOMEDICINE -- NANOSCALE PARTICLES IN NANOMEDICINE -- [A] Liposomes -- [B] Carbon Nanotubes -- [C] Quantum Dots and Cornell Dots -- [D] Dendrimers and Diamondoids -- [E] Magnetic Nanoparticles -- [F] Gold Nanoparticles (AuNP) -- [G] Solid Lipid Nanoparticles (SLN) -- [H] Polymeric Nanoparticles -- [I] Ceramic Nanoparticles -- [J] Microemulsions -- APPLICATIONS ON NANOMEDICINE IN HEALTH SECTOR -- [A] Nanosurgery -- [B] Bionanoimaging -- [C] Tissue Implants and Tissue Engineering -- [D] Targeted Drug Delivery and Therapy -- [E] Diseases Diagnosis -- SAFETY ASPECTS OF NANOMEDICINE -- CONCLUSION -- REFERENCES -- CHAPTER 7. CISGENESIS AND INTRAGENESIS -- ABSTRACT -- INTRODUCTION -- CLASSICAL/CONVENTIONAL PLANT BREEDING -- TRANSGENESIS.

CISGENESIS AND INTRAGENESIS -- ADVANTAGES OF CISGENESIS OVER CONVENTIONAL BREEDING AND TRANSGENESIS -- DRAWBACKS AND LIMITATIONS OF CISGENESIS -- (I) Random Insertion Site of the Gene -- (II) Mutation Caused in the Plant Genome -- APPLICATIONS OF CISGENESIS -- GM REGULATIONS AND CISGENESIS -- SAFETY ASPECT OF CISGENIC CROPS -- FUTURE OF CISGENIC CROPS -- REFERENCES -- CHAPTER 8. GENETICALLY MODIFIED CROPS AND ALLERGENICITY: MYTH OR REALITY -- ABSTRACT -- INTRODUCTION -- ADVANTAGES OF GENETICALLY MODIFIED CROPS -- SAFETY OF GENETICALLY MODIFIED CROPS -- NEED FOR SAFETY EVALUATION OF GM FOODS -- FOOD ALLERGY -- GENETICALLY MODIFIED FOODS AND ALLERGY -- ASSESSMENT OF ALLERGENIC POTENTIAL OF GENETICALLY MODIFIED FOODS -- GM CROPS AND ALLERGENICITY: CASE STUDIES AND RELATED CONTROVERSIES -- [A] GM Soybean -- [B] GM Pea -- [C] GM Maize Starlink -- [D] GM Maize -- SHEDDING THE NEGATIVE APPROACH -- CONCLUSION -- REFERENCES -- CHAPTER 9. GENETICALLY MODIFIED CROPS-ARE WE ENGINEERING DESTRUCTION? -- ABSTRACT -- INTRODUCTION -- ADVANTAGES OF GM CROPS/FOODS -- [A] Increased Nutritional Content -- [B] Increasing Food Production -- [C] Resistance to Abiotic Stresses -- [D] Resistance to Insect Pests, Diseases and Herbicides -- [E] Phytoremediation -- [F] Biopharmaceuticals -- NEGATIVE ASPECTS -- [A] Threat to Soil Fertility -- [B] Gene Transfer and Super Weeds -- [C] Human Health Risks -- [D] Risk to Other Life Forms -- [E] Effects on Biodiversity -- [F] Insect Resistant Crops -- REGULATION OF GM CROPS -- ETHICAL CONSIDERATIONS -- CONCLUSION -- REFERENCES -- CHAPTER 10. PHARMACOGENOMICS -- ABSTRACT -- INTRODUCTION -- PHARMACOGENETICS, PHARMACOGENOMICS AND PHARMACOTHERAPY -- CONVENTIONAL DRUG DEVELOPMENT -- ADVERSE DRUG REACTION [ADR] -- HISTORY OF PHARMACOGENOMICS -- TOOLS USED IN PHARMACOGENOMICS -- [A] Sequencing -- [B] Microarray.

PHARMACOGENOMICS AND PERSONALIZED MEDICINE -- CURRENT APPLICATIONS OF PHARMACOGENOMICS -- PHARMACEUTICAL INDUSTRY AND PHARMACOGENOMICS -- COST EFFECTIVENESS -- LIMITATIONS AND RISKS OF PHARMACOGENOMICS -- [A] Change in the Concept and Treatment of Disease -- [B] Acceptance by Public -- ETHICAL, SOCIAL AND LEGAL IMPLICATIONS -- [A] Regulation of Pharmacogenomics -- [B] Genetic Testing -- [C] Commercial Exploitation and IntellectualProperty of Pharmacogenetics Databanks -- PROMISE AND PROSPECTS -- REFERENCES -- CHAPTER 11. FUNCTIONAL FOODS AND NUTRACEUTICALS -- ABSTRACT -- INTRODUCTION -- WHAT ARE NUTRACEUTICALS AND FUNCTIONAL FOODS? -- HISTORICAL EVOLUTION OF MEDICINAL NUTRIENTS -- PLANTS AS FUNCTIONAL FOODS -- ECOLOGICAL PERSPECTIVES OF FUNCTIONAL FOODS -- BIOTECHNOLOGY AND FUNCTIONAL FOODS -- [A] Improvement in Fatty Acid Profile -- [B] Improvement in Protein Quality and Quantity -- [C] Improvement in Vitamin Content -- [D] Improvement in Carbohydrate -- REASONS FOR GROWING INTEREST IN FUNCTIONAL FOODS AND NUTRACEUTICALS -- REGULATION AND MARKETING OF NUTRACEUTICALS AND FUNCTIONAL FOODS -- NUTRACEUTICALS AND NANOTECHNOLOGY -- DEMAND FOR NUTRACEUTICALS -- ETHICS IN FUNCTIONAL FOODS AND NUTRACEUTICALS -- (i) Are Functional Foods Safe? -- (ii) Are Functional Foods Effective? -- (iii) Reliability and Trustworthiness of the Claims -- (iv) Are Functional Foods Affordable to the Common Man? -- (v) Socio-Cultural Dimension of Functional Foods -- OPPORTUNITIES AND CHALLENGES -- REFERENCES -- CHAPTER 12. PLANT MOLECULAR FARMING -- ABSTRACT -- INTRODUCTION -- HISTORY OF PLANT MOLECULAR FARMING -- USE OF PLANTS AS PRODUCTION SYSTEMS -- METHODS OF GENE TRANSFER TO PLANTS -- [A] Stable Nuclear Transformation -- [B] Plastid Transformation -- [C] Transient Expression Using Viral Vectors -- [D] Agroinfiltration -- [E] Magnifection.

PLANT SYSTEMS USED AS EXPRESSION PLATFORMS -- TYPES OF PHARMACEUTICAL COMPOUNDS -- (I) Plant Derived Human and Animal Vaccines -- (II) Plant Derived Antibodies -- (III) Pharmaceutical Proteins -- (IV) Industrial Enzymes and other Molecules -- (V) Plant Derived Secondary Metabolites -- CONSTRAINTS IN PLANT SYSTEM -- (I) High Cost of Downstream Processing -- (II) Low Yield of Foreign Protein -- RISKS AND CONCERNS -- COST EVALUATION OF RECOMBINANT BIOPHARMACEUTICALS -- REGULATION FOR PRODUCTION OF PHARMACEUTICAL CROPS -- FUTURE PROSPECTS -- REFERENCES -- INDEX.