Whole Genome Sequencing of Candida glabrata for Detection of Markers of Antifungal Drug Resistance
Title:
Whole Genome Sequencing of Candida glabrata for Detection of Markers of Antifungal Drug Resistance
Author:
Biswas, Chayanika
Personal Author:
Publication Information:
Cambridge, MA MyJoVE Corp 2016
Physical Description:
online resource (525 seconds)
Series:
Medicine
General Note:
Title from resource description page
Abstract:
This study implemented whole genome sequencing for analysis of mutations in genes conferring antifungal drug resistance in Candida glabrata. C. glabrata isolates resistant to echinocandins, azoles and 5-flucytosine, were sequenced to illustrate the methodology. Susceptibility profiles of the isolates correlated with presence or absence of specific mutation patterns in genes.
Reading Level:
For undergraduate, graduate, and professional students
Subject Term:
Electronic Access:
https://www.jove.com/t/56714