FrontMatter -- Preface -- Acknowledgments -- Contents -- Summary -- 1 Introduction -- 2 The Impact of Social and Cultural Environment on Health -- 3 Genetics and Health -- 4 Genetic, Environmental, and Personality Determinants of Health Risk Behaviors -- 5 Sex/Gender, Race/Ethnicity, and Health -- 6 Embedded Relationships Among Social, Behavioral, and Genetic Factors -- 7 Animal Models -- 8 Study Design and Analysis for Assessment of Interactions -- 9 Infrastructure -- 10 Ethical, Legal, and Social Implications -- 11 Conclusion -- APPENDIXES -- A Methodology: Data Collection and Analysis -- B Recommendation from the National Academy of Sciences/ National Academy of Engineering/ Institute of Medicine Report Facilitating Interdisciplinary Research -- C Social Environmental and Genetic Influences on Obesity and Obesity-Promoting Behaviors: Fostering Research Integration -- D The Interaction of Social, Behavioral, and Genetic Factors in Sickle Cell Disease -- E Modern Epidemiologic Approaches to Interaction: Applications to the Study of Genetic Interactions -- F Acronyms -- G Biographical Sketches -- Index.