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Synthesis and Characterization of Glycosides
Title:
Synthesis and Characterization of Glycosides
Author:
Brito-Arias, Marco. author.
ISBN:
9783319323107
Personal Author:
Edition:
2nd ed. 2016.
Physical Description:
XVII, 422 p. 487 illus., 75 illus. in color. online resource.
Contents:
Introduction -- O-Glycoside Formation -- N-glycosides -- Nucleotide Mimetics -- C-glycosides -- Glycoconjugates -- Hydrolysis of Glycosides -- Nuclear Magnetic Resonance of Glycosides -- X-Ray Diffraction of Glycosides -- Mass Spectrometry of Glycosides -- Docking studies of Glycosides -- Index.
Abstract:
This second edition is a short and comprehensive study on the best known approaches for preparing the main types of glycosides. It covers synthetic pathways of challenging glycosides known as antiviral or antineoplastic drugs, and synthetic substrates used for enzymatic detection, including those used for detection of gene markers in plant biotechnology. The author pays special attention to the structural characterization of glycosides and provides the basic tools for the structural assignment through NMR, X-Ray and mass spectra techniques. The book also covers strategies for preparation of antiviral and antineoplastic drugs included in a drug design course.
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