FrontMatter -- Preface -- Acknowledgments -- Contents -- Summary -- 1 Introduction -- 2 Domains of Human Vulnerability and Global-Scale Processes -- 3 Climate Change Metrics at the Intersection of the Human and Earth Systems -- 4 Final Thoughts -- References -- Appendix A: Statement of Task -- Appendix B: Working Document: Topical Panel Breakouts -- Appendix C: Committee and Staff Biosketches.