Multidimensional Coculture System to Model Lung Squamous Carcinoma Progression
Title:
Multidimensional Coculture System to Model Lung Squamous Carcinoma Progression
Author:
Chen, Shuang
Personal Author:
Publication Information:
Cambridge, MA MyJoVE Corp 2016
Physical Description:
online resource (473 seconds)
Series:
Cancer Research
General Note:
Title from resource description page
Abstract:
An in vitro model system was developed to capture tissue architectural changes during lung squamous carcinoma (LUSC) progression in a 3-dimensional (3D) co-culture with cancer-associated fibroblasts (CAFs). This organoid system provides a unique platform to investigate the roles of diverse tumor cell-intrinsic and extrinsic changes that modulate the tumor phenotype.
Reading Level:
For undergraduate, graduate, and professional students
Subject Term:
Electronic Access:
https://www.jove.com/t/60644