Half Title page -- Title page -- Copyright page -- Preface -- Part 1: System Biology and Translational Medicine -- Chapter 1: Aberrant Signaling Pathways -- 1.1 Cancer -- 1.2 Pathways Deregulated in Cancer: Introduction -- 1.3 Introduction to Nanotechnology -- 1.4 Current Uses in Cancer Diagnostic -- Acknowledgment -- References -- Chapter 2: Application of Nanoparticles in Cancer Treatment -- 2.1 Introduction -- 2.2 Nanoparticles in Cancer Treatment -- 2.3 Nanoparticle Platforms as Drug Delivery Systems for Cancer Therapy -- 2.4 Theranostic Nanomedicine -- 2.5 Selective Drug Delivery and Encapsulation for Chemotherapy -- 2.6 Stimuli-Sensitive Nanopreparations -- 2.7 Multifunctional Nanopreparations -- 2.8 Cancer Nanotechnology: Future and Challenges -- References -- Chapter 3: Biomacromolecule-Gated Mesoporous Silica Drug Delivery Systems for Stimuli-Responsive Controlled Release -- 3.1 Introduction -- 3.2 Protein-Gated MSN Drug Delivery Systems -- 3.3 DNA-Gated MSN Drug Delivery Systems -- 3.4 Conclusions and Perspectives -- Acknowledgments -- References -- Chapter 4: Construction of Functional DNA Nanostructures for Theranostic Applications -- 4.1 The Progress of Structural DNA Nanotechnology -- 4.2 DNA Nanostructures for Diagnostics -- 4.3 DNA Nanostructures for Diagnostics on the Interface -- 4.4 Diagnostic in Homogeneous Solution -- 4.5 DNA Nanostructures for Therapeutics -- 4.6 Integration of Diagnosis and Therapy: Smart DNA Theranostic Nanodevices -- 4.7 Targeted Delivery -- 4.8 Controlled/Triggered Release -- 4.9 Summary and Perspectives -- References -- Part 2: Imaging and Therapeutics -- Chapter 5: Dimercaptosuccinic Acid-Coated Magnetic Nanoparticles as a Localized Delivery System in Cancer Immunotherapy -- 5.1 Introduction -- 5.2 Nanoparticle Detection and Quantification: In Vitro and In Vivo Techniques.

5.3 Evaluation of Nanoparticle-Induced Toxicity -- 5.4 Magnetic Targeting of Nanoparticles -- 5.5 A Specific Example: DMSA-Coated Magnetic Nanoparticles -- 5.6 Conclusions -- Acknowledgments -- References -- Chapter 6: Cardiovascular Nanomedicine -- 6.1 Introduction -- 6.2 Nanoscale Cardiovascular Diagnostics -- 6.3 Nanotechnology in Cardiovascular Therapeutics -- 6.4 Nanotechnology in the Surgery of Cardiovascular Disease -- 6.5 Conclusion -- References -- Chapter 7: Chitosan-based Interpenetrating Polymeric Network Systems for Sustained Drug Release -- 7.1 Introduction -- 7.2 IPNs and Their Uses in Drug Delivery -- 7.3 Chitosan -- 7.4 Chitosan-Tamarind Seed Polysaccharide IPN Microparticles and Matrix Tablets for Sustained Release of Aceclofenac -- 7.5 Chitosan-Hydroxyethyl Cellulose IPN Microspheres of Isoniazid -- 7.6 Chitosan-Methyl Cellulose IPN Microspheres of Theophylline -- 7.7 Chitosan-Acrylamide-Grafted-Poly(Vinyl Alcohol) and Hydrolyzed Acrylamide-Grafted-Poly(Vinyl Alcohol) IPN Microgels of Cefadroxil -- 7.8 Chitosan-Poly(N-Isopropylacrylamide) IPN Discs of Diclofenac Sodium -- 7.9 Chitosan-Poly(Ethylene Oxide-Grafted-Acrylamide) Semi-IPN Hydrogel Microspheres of Capecitabine -- 7.10 Acrylamide-Grafted Dextran-Chitosan Semi-IPN Microspheres of Acyclovir -- 7.11 Chitosan-Acrylamide-Grafted Hydroxyethylcellulose Semi-IPN Microspheres of Diclofenac Sodium -- 7.12 Poly [N-Acryloylglycine-Chitosan] IPN Hydrogel of 5-Fluorouracil -- 7.13 Chitosan-N,N′-Dimethylacrylamide Semi-IPN Microspheres of Chlorothiazide -- 7.14 Conclusion -- References -- Chapter 8: Nanocapsules in Biomedicine -- 8.1 Nanocapsules: A Novel Nano-Drug Delivery System -- 8.2 Magic Bullets: Nanocapsules in Future Medicine -- 8.3 In Vitro Applications of Nanocapsules -- 8.4 In Vivo Applications of Nanocapsules -- 8.5 Conclusions -- References.

Chapter 9: Chitosan-based Polyelectrolyte Complexes -- 9.1 Introduction -- 9.2 Chitosans: Chemical Structure, Physicochemical Properties, and Toxicological and Regulatory Aspects -- 9.3 Polyelectrolyte Complexes: Theoretical Background, Structure, and Basic Properties -- 9.4 Chitosan-based Polyelectrolyte Complexes in Particulate Drug Carriers -- 9.5 Characterization of Chitosan-Based PECs and Chitosan-based PEC Particulate Drug Carriers -- 9.6 Conclusion -- Acknowledgment -- References -- Part 3: Diagnostics and Featured Prognostics -- Chapter 10: Non-invasive Glucose Biosensors Based on Nanomaterials -- 10.1 Diabetes and Its Prevalence -- 10.2 Importance of Glucose Monitoring -- 10.3 Glucose Measurement Methods -- 10.4 Non-invasive Glucose Determination -- 10.5 Glucose Biosensors -- 10.6 New Generation of Non-invasive Glucose Biosensors-Based Nanomaterials -- 10.7 Future Perspective in Glucose Monitoring -- 10.8 Conclusion -- References -- Chapter 11: Self-Directed Assembly of Nanoparticles -- 11.1 Introduction -- 11.2 Self-Assembly through Molecular Interactions/Forces -- 11.3 Hydrogen-Bonding Interactions -- 11.4 Directed Self-Assembly by External Forces -- 11.5 Conclusion -- Acknowledgment -- References -- Index.