Front Cover -- The Vitamins -- Copyright Page -- Dedication Page -- Contents -- Preface -- Preface to the Second Edition -- Preface to the First Edition -- How to Use This Book -- Part I: Perspectives on the Vitamins in Nutrition -- Chapter I: What is a Vitamin? -- I. Thinking about Vitamins -- II. Vitamin: A Revolutionary Concept -- III. An Operating Definition of a Vitamin -- IV. The Recognized Vitamins -- Study Questions -- Chapter 2: Discovery of the Vitamins -- I. The Emergence of Nutrition as a Science -- II. The Process of Discovery in Nutritional Science -- III. The Empirical Phase of Vitamin Discovery -- IV. The Experimental Phase of Vitamin Discovery -- V. The Vitamine Theory -- VI. Elucidation of the Vitamins -- VII. Vitamin Terminology -- VIII. Other Factors Sometimes Called Vitamins -- IX. The Modern History of the Vitamins -- Study Questions and Exercises -- Recommended Reading -- Chapter 3: Chemical and Physiological Properties of the Vitamins -- I. Chemical and Physical Properties of the Vitamins -- II. Vitamin A -- III. Vitamin D -- IV. Vitamin E -- V. Vitamin K -- VI. Vitamin C -- VII. Thiamin -- VIII. Riboflavin -- IX. Niacin -- X. Vitamin B6 -- XI. Biotin -- XII. Pantothenic Acid -- XIII. Folate -- XIV. Vitamin B12 -- XV. General Properties of the Vitamins -- XVI. Physiological Utilization of the Vitamins -- XVII. Metabolism of the Vitamins -- XVIII. Metabolic Functions of the Vitamins -- Study Questions and Exercises -- Recommended Reading -- Chapter 4: Vitamin Deficiency -- I. The Concept of Vitamin Deficiency -- II. The Many Causes of Vitamin Deficiencies -- III. Clinical Manifestations of Vitamin Deficiencies -- IV. Vitamin Deficiency Diseases: Manifestations of Biochemical Lesions -- Study Questions and Exercises -- Recommended Reading -- Part II: Considering the Individual Vitamins -- Chapter 5: Vitamin A.

I. Significance of Vitamin A -- II. Sources of Vitamin A -- III. Absorption of Vitamin A -- IV. Transport of Vitamin A -- V. Metabolism of Vitamin A -- VI. Excretion of Vitamin A -- VII. Metabolic Functions of Vitamin A -- VIII. Vitamin A Deficiency -- IX. Vitamin A Toxicity -- X. Case Studies -- Study Questions and Exercises -- Recommended Reading -- Chapter 6: Vitamin D -- I. Significance of Vitamin D -- II. Sources of Vitamin D -- III. Enteric Absorption of Vitamin D -- IV. Transport of Vitamin D -- V. Metabolism of Vitamin D -- VI. Metabolic Functions of Vitamin D -- VII. Vitamin D Deficiency -- VIII. Vitamin D Toxicity -- IX. Case Studies -- Study Questions and Exercises -- Recommended Reading -- Chapter 7: Vitamin E -- I. The Significance of Vitamin E -- II. Sources of Vitamin E -- III. Absorption of Vitamin E -- IV. Transport of Vitamin E -- V. Metabolism of Vitamin E -- VI. Metabolic Functions of Vitamin E -- VII. Vitamin K Deficiency -- VIII. Pharmacologic Uses of Vitamin E -- IX. Vitamin K Toxicity -- X. Case Studies -- Study Questions and Exercises -- Recommended Reading -- Chapter 8: Vitamin K -- I. The Significance of Vitamin K -- II. Sources of Vitamin K -- III. Absorption of Vitamin K -- IV. Transport of Vitamin K -- V. Metabolism of Vitamin K -- VI. Metabolic Functions of Vitamin K -- VII. Vitamin K Deficiency -- VIII. Vitamin K Toxicity -- IX. Case Studies -- Study Questions and Exercises -- Recommended Reading -- Chapter 9: Vitamin C -- I. The Significance of Vitamin C -- II. Sources of Vitamin C -- III. Absorption of Vitamin C -- IV. Transport of Vitamin C -- V. Metabolism of Vitamin C -- VI. Metabolic Functions of Vitamin C -- VII. Vitamin C Deficiency -- VIII. Pharmacological Uses of Vitamin C -- IX. Vitamin C Toxicity -- X. Case Studies -- Study Questions and Exercises -- Recommended Reading -- Chapter 10: Thiamin.

I. The Significance of Thiamin -- II. Sources of Thiamin -- III. Absorption of Thiamin -- IV. Transport of Thiamin -- V. Metabolism of Thiamin -- VI. Metabolic Functions of Thiamin -- VII. Thiamin Deficiency -- VIII. Thiamin Toxicity -- IX. Case Studies -- Study Questions and Exercises -- Recommended Reading -- Chapter 11: Riboflavin -- I. The Significance of Riboflavin -- II. Sources of Riboflavin -- III. Absorption of Riboflavin -- IV. Transport of Riboflavin -- V. Metabolism of Riboflavin -- VI. Metabolic Functions of Riboflavin -- VII. Riboflavin Deficiency -- VIII. Riboflavin Toxicity -- IX. Case Study -- Study Questions and Exercises -- Recommended Reading -- Chapter 12: Niacin -- I. The Significance of Niacin -- II. Sources of Niacin -- III. Absorption of Niacin -- IV. Transport of Niacin -- V. Metabolism of Niacin -- VI. Metabolic Functions of Niacin -- VII. Niacin Deficiency -- VIII. Pharmacologic Uses of Niacin -- IX. Niacin Toxicity -- X. Case Study -- Study Questions and Exercises -- Recommended Reading -- Chapter 13: Vitamin B6 -- I. The Significance of Vitamin B6 -- II. Sources of Vitamin B6 -- III. Absorption of Vitamin B6 -- IV. Transport of Vitamin B6 -- V. Metabolism of Vitamin B6 -- VI. Metabolic Functions of Vitamin B6 -- VII. Vitamin B6 Deficiency -- VIII. Pharmacologic Uses of Vitamin B6 -- IX. Vitamin B6 Toxicity -- X. Case Studies -- Study Questions and Exercises -- Recommended Reading -- Chapter 14: Biotin -- I. The Significance of Biotin -- II. Sources of Biotin -- III. Absorption of Biotin -- IV. Transport of Biotin -- V. Metabolism of Biotin -- VI. Metabolic Functions of Biotin -- VII. Biotin Deficiency -- VIII. Biotin Toxicity -- IX. Case Study -- Study Questions and Exercises -- Recommended Reading -- Chapter 15: Pantothenic Acid -- I. The Significance of Pantothenic Acid -- II. Sources of Pantothenic Acid.

III. Absorption of Pantothenic Acid -- IV. Transport of Pantothenic Acid -- V. Metabolism of Pantothenic Acid -- VI. Metabolic Functions of Pantothenic Acid -- VII. Pantothenic Acid Deficiency -- VIII. Pantothenic Acid Toxicity -- IX. Case Study -- Study Questions and Exercises -- Recommended Reading -- Chapter 16: Folate -- I. The Significance of Folate -- II. Sources of Folate -- III. Absorption of Folate -- IV. Transport of Folate -- V. Metabolism of Folate -- VI. Metabolic Functions of Folate -- VII. Folate Deficiency -- VIII. Pharmacologic Uses of Folate -- IX. Folate Toxicity -- X. Case Study -- Study Questions and Exercises -- Recommended Reading -- Chapter 17: Vitamin B12 -- I. The Significance of Vitamin B12 -- II. Sources of Vitamin B12 -- III. Absorption of Vitamin B12 -- IV. Transport of Vitamin B12 -- V. Metabolism of Vitamin B12 -- VI. Metabolic Functions of Vitamin B12 -- VII. Vitamin B12 Deficiency -- VIII. Vitamin B12 Toxicity -- IX. Case Study -- Study Questions and Exercises -- Recommended Reading -- Chapter 18: Quasi-vitamins -- I. Is the List of Vitamins Complete? -- II. Choline -- III. Carnitine -- IV. myo-Inositol -- V. Pyrroloquinoline Quinone -- VI. Ubiquinones -- VII. Flavonoids -- VIII. Non-Provitamin A Carotenoids -- IX. Orotic Acid -- X. p-Aminobenzoic Acid -- XI. Lipoic Acid -- XII. Ineffective Factors -- XIII. Unidentified Growth Factors -- Study Questions and Exercises -- Recommended Reading -- Part III: Using Current Knowledge of the Vitamins -- Chapter 19: Sources of the Vitamins -- I. Vitamins in Foods -- II. Vitamin Contents of Feedstuffs -- III. Predicting Vitamin Contents -- IV. Vitamin Bioavailability -- V. Vitamin Losses -- VI. Vitamin Supplementation and Fortification of Foods -- VII. Vitamins in Human Diets -- VIII. Vitamin Supplements -- IX. Vitamin Labeling of Foods -- X. Vitamins in Livestock Feeds.

Study Questions and Exercises -- Recommended Reading -- Chapter 20: Assessing Vitamin Status -- I. General Aspects of Nutritional Assessment -- II. Assessment of Vitamin Status -- III. Vitamin Status of Human Populations -- Study Questions and Exercises -- Recommended Reading -- Chapter 21: Quantifying Vitamin Needs -- I. Dietary Standards -- II. Determining Dietary Standards for Vitamins -- III. Factors Affecting Vitamin Requirements -- IV. Vitamin Allowances for Humans -- V. Vitamin Allowances for Animals -- Study Questions and Exercises -- Recommended Reading -- Chapter 22: Vitamin Safety -- I. Uses of Vitamins above Required Levels -- II. Hazards of Excessive Vitamin Intakes -- III. Signs of Hypervitaminoses -- IV. Safe Intakes of Vitamins -- Study Questions and Exercises -- Recommended Reading -- Appendices -- Appendix A: Vitamin Terminology: Past and Present -- Appendix B: Original Reports for Case Studies -- Appendix C: A Core of Current Vitamin Research Literature -- Appendix D: Vitamin Contents of Foods -- Appendix E: Vitamin Contents of Feedstuffs -- Index.