Cover image for Xeno : The Promise of Transplanting Animal Organs into Humans.
Xeno : The Promise of Transplanting Animal Organs into Humans.
Title:
Xeno : The Promise of Transplanting Animal Organs into Humans.
Author:
Cooper, David K. C. M.D.
ISBN:
9780195351828
Personal Author:
Physical Description:
1 online resource (299 pages)
Contents:
Contents -- An appreciation -- Foreword -- Preface: The next great medical revolution? -- Acknowledgments -- 1 The End of the Night Shift: Organ transplantation today and tomorrow -- 2 Animal Attraction: Supply and demand in the world of organ transplantation -- 3 From Icarus to the First Heart Transplant: Man's early attempts to bridge the species gap -- 4 All Animals Are Equal, but Some Are More Equal than Others: The choice of donor -- 5 Zero Tolerance: The rejection of animal organs -- 6 A Spoonful of Sugar: Preventing rejection -- 7 The "Humanized" Pig: Manipulating the genes of the donor -- 8 The Immunological Holy Grail: Tolerance -- 9 From Diabetes to Alzheimer's: Cells that will make a difference -- 10 The Discordant Concert: Will the transplanted organ work? -- 11 The Hottest Zone: The fear of an AIDS-like epidemic -- 12 Guinea Pigs: The selection of the first patients -- 13 Animal Rights and Human Wrongs: Ethical concerns -- 14 Protecting the Public: Government regulations and safeguards -- 15 Judgment Day: Potential legal problems -- 16 The Ultimate Piggy Bank: Animal transplants and health care economics -- 17 A Vision with a Task -- Appendix -- Glossary of selected biomedical terms -- A -- B -- C -- D -- E -- F -- G -- H -- I -- M -- N -- O -- P -- R -- S -- T -- V -- W -- X -- Z -- Bibliography -- Index -- A -- B -- C -- D -- E -- F -- G -- H -- I -- J -- K -- L -- M -- N -- O -- P -- Q -- R -- S -- T -- U -- V -- W -- X -- Y -- Z.
Abstract:
The majority of patients in need of organ transplants do not survive long enough for a suitable human organ to become available. Xenotransplantation, the transplantation of animal organs into humans, has attracted substantial media attention. If, as appears likely, it proves possible to "humanize" animal organs and evade the problems of rejection, in the coming few years there will be a tremendous increase in this procedure, mostly using organs from animals specially grown for their harvestable organs. This book will lay out the potential and promise of the technique, the history of organ transplantation, the technical problems and breakthroughs in overcoming immune rejection, and typing and humanizing donor organs for transplantation. The ethical questions about growing animals specifically for organ harvest, and the substantial public health concern from the certainty that animal viruses will be passaged into humans with the donated organs, will be fully discussed. The authors are among the leaders of the field of xenotransplantation.
Local Note:
Electronic reproduction. Ann Arbor, Michigan : ProQuest Ebook Central, 2017. Available via World Wide Web. Access may be limited to ProQuest Ebook Central affiliated libraries.
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