FrontMatter -- Preface -- Acknowledgment of Reviewers -- Contents -- Summary -- 1 Overview of the Science Mission Directorate's Mission-Enabling Activities -- 2 Assessment of NASA's Mission-Enabling Activities -- 3 Principles and Metrics for Managing Effective Mission-Enabling Portfolios -- 4 Maximizing Program Effectiveness Through Strategic Management -- 5 Consolidated Findings and Recommendations -- Appendixes -- Appendix A: Statement of Task -- Appendix B: Presentations to the Committee -- Appendix C: Traceability of Mission-Enabling Activities from Strategic Goals -- Appendix D: Benchmarking High-Risk/High-Payoff Research -- Appendix E: Committee and Staff Biographical Information.