HANDBOOK OF NEUROPSYCHIATRY RESEARCH -- HANDBOOK OF NEUROPSYCHIATRY RESEARCH -- CONTENTS -- PREFACE -- Chapter 1PROLACTINOMAS, PRL & WEIGHT GAIN -- Abstract -- Abbreviations -- Introduction -- Prolactinomas and Weight Gain -- Prolactin and Adipocytes -- Brown Adipose Tissue -- Metabolic Enzyme Activity -- Indirect Influence -- Adipocyte Differentiation -- Antiadipogenic Effects -- PRL Influence on Adipokines -- Local Prolactin Secretion by the Adipocytes -- Prolactin and Appetite -- Prolactin Secretion in Obesity -- Disruption to the Dopamine Control Pathwayand Weight Gain -- Dopamine Agonists -- Conclusion -- References -- Chapter 2CLINICAL AND PATHOLOGICALCHARACTERISTICS OF PICK'S DISEASE ANDFRONTOTEMPORAL LOBAR DEGENERATIONWITH TDP-43-POSITIVE INCLUSIONS -- Abstract -- I. Introduction -- II. FTLD with TDP-43-Positive Inclusions (FTLD-TDP) -- II.1. Historical Background -- II.2. Genetic and Histopathological Features -- II.3. Clinical Features in PGRN-Linked FTLD-TDP -- II.4. Clinical Features in Sporadic FTLD-TDP -- III. FTLD with Tau-Positive Pick Bodies (Pick's Disease) -- III.1. Pick Bodies -- III.2. Clinical features in Pick's Disease -- IV. Evolving Patterns of Clinical Syndromes in SporadicFTLD-TDP and Pick's Disease -- V. Clinicopathological Correlation in FTLD-TDP andPick's Disease -- VII. Atrophy Patterns in FTLD Patients: Recent Findingsof Volumetric MRI -- VIII. Potential Biochemical Markers in FTLD -- IX. Conclusion -- Acknowledgement -- References -- Chapter 3INTERVENTIONS FOR AFFECTIVE ANDBEHAVIOURAL DISTURBANCES IN ACQUIREDBRAIN INJURY: A CONCEPTUAL FRAMEWORKBASED ON THE STAGES OF CHANGE THEORY -- Abstract -- Inrtoduction -- The Prevalence and Presentation of Affective & BehaviouralDisturbances in ABI -- Review of Treatment Approaches for Emotional and BehaviouralDifficulties in ABI.

Readiness for Change - Review of The Stages of Change Theory -- Tailoring Treatment Approaches - Application of the Stages ofChange Theory to ABI -- Conclusion -- References -- Chapter 4SEQUENTIAL EXPRESSION OF IMPAIREDPSYCHOMOTOR AND SENSORIMOTORACTIVITIES IN RODENTS DURINGAMPHETAMINE WITHDRAWAL -- Abstract -- Introduction -- Behavioral Consequences of AMPH Withdrawal inRodents -- Spontaneous Locomotion and other Behaviors Observed in OpenField -- Forced Swimming Test -- Tail Suspension Test -- Prepulse Inhibition -- Conditioned Fear -- Sexual Behavior -- Sequential Expression of Impaired Psychomotor and SensorimotorActivities and Related Behaviors -- Future Directions and Applications of AMPH Withdrawal -- Acknowledgments -- References -- Chapter 5ASSOCIATION BETWEEN SALIVARYAMYLASE, CORTISOL AND STRESS -- Abstract -- Introduction -- Relationship between the SAM System and Stress -- Relationship between the HPA Axis and Stress -- References -- Chapter 6SEROTONERGIC RECEPTORS IN THE CENTRALNERVOUS SYSTEM - A BRIEF REVIEW -- Abstract -- References -- Chapter 7THE NEXT MAJOR NEUROPSYCHOLOGICALAND NEUROPSYCHIATRICALBREAKTHROUGH: ALZHEIMER'S DISEASE -- Abstract -- The Next Major Neuropsychological Breakthrough:Alzheimer's Disease -- Causal (Risk) Factors of AD -- Diagnosis of AD -- Conclusions -- References -- Chapter 8NEUROLOGY, PSYCHIATRY AND GENETICS:INTERRELATIONSHIP -- Abstract -- Introduction -- Neurology and Genetics -- Psychiatry and Genetics -- Genetics in Neuropsychiatry -- References -- Chapter 9HOW CAN BIOINFORMATICS HELP STUDIESIN NEUROPSYCHIATRY? -- Abstract -- Introduction -- Usefulness of Bioinformatics in Neuropsychiatric Studies -- A. Study of the Mutation on Genetic and Protein Level -- B. Study on Physiogenomics -- Conclusion -- References.

Chapter10EXTRACTINGDISCRIMINANTINFORMATIONFROMNEUROIMAGES:AMULTIVARIATECOMPUTATIONALFRAMEWORKTOANALYZETHEWHOLEHUMANBRAIN -- Abstract -- 1.Introduction -- 2.AStatisticalPatternRecognitionSystem -- 3.TheMultivariateComputationalFramework -- 3.1.SpatialNormalization(orPre-Processing) -- 3.2.PCA(orFeatureExtraction) -- 3.3.LDA(orHyperplaneClassification) -- 4.DesignoftheExperiments -- 5.CaseStudies -- 5.1.MRIDifferencesinADPatientsRelativelytoControls -- 5.1.1.Mass-univariateStatisticalAnalysis -- TemplateCustomization,TissueSegmentationandSmoothing -- ExtractingVoxel-by-VoxelDifferencesfromtheMRISamples -- 5.1.2.MultivariateStatisticalAnalysis -- EvaluatingtheMultivariateSeparationbetweentheADandControlSam-pleGroups -- EvaluatingtheDiagnosticCoherenceoftheSeparatingHyper-Plane -- ExtractingMultivariateDiscriminativeInformationfromtheMRISam-ples -- 5.2.MRIMulti-linearAnalysisofNormalSubjects -- MRImagesDescription,NormalizationandSegmentation -- PerformingandEvaluatingtheMulti-linearDiscriminantAnalyzes -- 6.Conclusion -- Acknowledgment -- References -- INDEX -- Blank Page.