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Stem Cell Therapy and Tissue Engineering for Cardiovascular Repair From Basic Research to Clinical Applications
Title:
Stem Cell Therapy and Tissue Engineering for Cardiovascular Repair From Basic Research to Clinical Applications
Author:
Dib, Nabil. editor.
ISBN:
9780387309392
Physical Description:
XIX, 335 p. online resource.
Contents:
Myocardial Remodeling -- Ventricular Remodeling In Ischemic Cardiomyopathy -- Myocardial Regeneration -- Myocardial Regeneration: Which Cell and Why -- Cardiac Stem Cells -- Cardiac Stem Cells for Myocardial Regeneration -- Skeletal Myoblast -- A Historic Recapitulation of Myoblast Transplantation -- Myoblast Cell Transplantation: Preclinical Studies -- Skeletal Myoblasts: The European Experience -- Skeletal Myoblasts: The U.S. Experience -- Progenitor Cells -- Progenitor Cells for Cardiac Regeneration -- Bone Marrow -- Bone Marrow-Derived Stem Cell for Myocardial Regeneration: Preclinical Experience -- Bone Marrow Derived Stem Cells for Myocardial Regeneration: Clinical Experience, Surgical Delivery -- Autologous Mononuclear Bone Marrow Cell Transplantion for Myocardial Infarction: The German Experience -- Autologous Mononuclear Bone Marrow Transplantation for Myocardial Infarction: The Spanish Experience -- Mobilizing Bone Marrow Stem Cells for Myocardial Repair After Acute Myocardial Infarction -- Percutaneous Stem Cell Transplantation -- Percutaneous Myoblast Transplantation: Steps In Translational Research -- A Porcine Model of Myocardial Infarction for Evaluation of Cell Transplantation -- Tissue Engineering -- Tissue Engineering for Myocardial Regeneration -- Functional and Electrophysiological Assessment after Cell Tranplantation -- The Role of Pet Scan in Stem Cell Therapy -- The Measurement of Systolic Function in the Mammalian Heart -- Electrophysiological Aspects of Cell Transplantation -- Regulatory Perspective -- Regulatory Considerations in Manufacturing, Product Testing, and Preclinical Development of Cellular Products for Cardiac Repair.
Abstract:
Stem Cell Therapy & Tissue Engineering for Cardiovascular Repair Dib, Taylor, Diethrich Stem Cell Therapy & Tissue Engineering for Cardiovascular Repair serves as an essential reference material covering these emerging technologies in cardiovascular research. Written by prominent world authorities presenting commissioned summaries, Stem Cell Therapy & Tissue Engineering for Cardiovascular Repair discusses the spectrum of stem cell and tissue engineering from basic research to clinical applications, offering a comprehensive, integrated reference.  Key Features: Covers the fields of translational research and clinical applications including, - Pertinent information on cell isolation, expansion, and delivery, both in animals and humans - Overview of embryonic, bone marrow, and myoblast cell culturing and transplantation - Detailed explanations of the FDA regulatory pathways for cell production - Preclinical requirements for investigational new drug applications. - Regulatory requirements that can be applied to a variety of stem cell therapies Stem Cell Therapy & Tissue Engineering for Cardiovascular Repair is essential for all cardiovascular research scientists, clinical researchers, and industry professionals wishing to take advantage of the latest and greatest in the continuously emerging field of stem cell therapy and tissue engineering for cardiovascular repair. the Editors: Nabil Dib, M.D., M.Sc, F.A.C.C, Director of Interventional Cardiology Research, Arizona Heart Institute and Heart Hospital, Phoenix, Arizona Doris Taylor, Ph.D., Bakken Professor, Director, Center for Cardiovascular Repair, University of Minnesota, Minneapolis, Minnesota Edward B. Diethrich, M.D., Medical Director, Arizona Heart Institute and Heart Hospital, Phoenix, Arizona.
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