ON-FARM STRATEGIES TO CONTROL FOODBORNE PATHOGENS -- ON-FARM STRATEGIES TO CONTROL FOODBORNE PATHOGENS -- CONTENTS -- PREFACE -- INTRODUCTION -- REFERENCES -- PRE-HARVEST FOOD SAFETY: THE PAST AND THE FUTURE -- ABSTRACT -- INTRODUCTION TO FOOD SAFETY -- BACKGROUND ON PREHARVEST FOOD SAFETY -- PREHARVEST FOOD SAFETY INTERVENTIONS, CONTROLS, AND MITIGATIONS -- PREHARVEST: LEARNING FROM THE PAST AND LOOKING TO FUTURE -- REFERENCES -- ETHICS AND PREHARVEST FOOD SAFETY -- FOOD SAFETY PROBLEMS ON THE FARM -- What Role Do Large-Scale Confinement Facilities Play in Foodborne Pathogen Dissemination? -- Organic Production is Better than Modern Industrial Systems, Right? -- WHAT CAN WE DO? -- WHO WILL BE PAYING FOR THESE IMPROVEMENTS? -- CONCLUSIONS -- REFERENCES -- INTERVENTIONS TO IMPROVE THE SAFETY OF MILK PRODUCTION -- ABSTRACT -- INTRODUCTION -- ANTIBIOTIC USE FOR TREATMENT AND PREVENTION OF MASTITIS -- ISSUES ASSOCIATED WITH ANTIBIOTIC USE -- Antibiotic Residues Associated with Antibiotic Use in Dairy Cows -- Antimicrobial Resistance Associated with Antibiotic Use in Dairy Cows -- ASSESSING MILK QUALITY AND MONITORING FOR PATHOGENS IN BULK TANK MILK -- MILKING TIME HYGIENE AND GOOD HUSBANDRY/PRODUCTION PRACTICES -- VACCINES TO PREVENT MASTITIS -- Mastitis Caused by Gram-Positive Pathogens -- Mastitis Caused by Gram-Negative Pathogens -- DNA/DNA-Protein Vaccines for Prevention of Mastitis -- Vaccination with Recombinant Proteins -- VACCINES TO REDUCE SHEDDING OF FOODBORNE PATHOGENS -- HAZARDS ASSOCIATED WITH RAW MILK AND MILK PASTEURIZATION -- Prevalence of Foodborne Pathogens in Raw Bovine Milk and Milk Products -- Prevalence of Mastitis Pathogens in Raw Milk -- INTERVENTION STRATEGIES ON THE HORIZON TO IMPROVE THE SAFETY OF MILK PRODUCTION -- Transgenic Approaches to Combat Mastitis -- Marker Assisted Selection for Mastitis Resistance.

Role of Bovine Leucocyte Antigen Gene Alleles (Bola-DRB3) in Mastitis Resistance -- Use of Probiotics for the Control of Mastitis -- Use of Bacteria as Competitive Exclusion (CE), Direct-Fed Microbials for Mastitis Control -- Foodborne Pathogen Reduction Using Probiotics -- Use of Bacteriocins from Gram-Positive Bacteria in the Treatment of Mastitis -- Other Bacteriocins with Potential Use in Mastitis Treatment -- Potential for Bacteriocins from Gram-Negative Bacteria for Use in Mastitis Control -- Use of Bacteriophages in Control of Mastitis and Foodborne Pathogens -- Other Alternative Therapies to Use of Antibiotics for Mastitis Control -- CONCLUSION -- REFERENCES -- BACTERIOPHAGE AS A PRE-HARVEST PATHOGEN REDUCTION STRATEGY -- 1. BACTERIOPHAGES AND THEIR FUNCTION -- 2. ADVANTAGES OF PHAGES FOR PRE-HARVEST BIOCONTROL OF PATHOGENIC BACTERIA -- 3. REGULATORY ENVIRONMENT FOR PHAGE BIOCONTROL - CONCERNS AND SOLUTIONS -- 4. FACTORS AFFECTING THE SUCCESS OF PHAGE BIOCONTROL -- A. Replication Threshold and Physical or Biological Barriers -- B. Method of Phage Administration -- C. Competitive Interference and Endogenous Phage -- D. Dosage Rates for Effective Phage Biocontrol -- 5. PAST IN VIVO PHAGE BIOCONTROL STUDIES AND BACTERIAL PATHOGENS TARGETED -- A. Chickens -- B. Pigs -- C. Cattle and Sheep -- 6. FUTURE DIRECTIONS -- A. Multivalent Phages -- B. Phages in Aquaculture -- C. Phages for the Environment -- D. Toward the Goal of Consistently Effective Phage Biocontrol -- REFERENCES -- PROBIOTICS IN SWINE PRODUCTION -- ABSTRACT -- INTRODUCTION -- FOODBORNE PATHOGENS ASSOCIATED WITH SWINE -- Salmonella -- Campylobacter -- Escherichia Coli -- SWINE GASTROINTESTINAL MICROFLORA -- Introduction -- Porcine Gastrointestinal Tract (GIT) -- Identification of Specific Swine Gut Microflora and Their Development in the GIT -- PROBIOTICS IN SWINE.

General Concepts -- Mechanism of Action -- Structural and Functional Properties of Intestinal Mucosa -- Immunologic Functions -- Metabolic Functions -- Protective Functions -- APPLICATIONS OF PROBIOTICS N SWINE PRODUCTION -- Bacterial Based Probiotics -- Application of Yeasts as Probiotics in Swine -- Limitation of Swine Probiotics -- FUTURE DIRECTIONS -- CONCLUSIONS -- REFERENCES -- VACCINATION AS A METHOD OF E. COLI O157:H7 REDUCTION IN FEEDLOT CATTLE -- ABSTRACT -- INTRODUCTION -- STEC O157 VACCINE CHALLENGE EXPERIMENTS -- FIELD EFFICACY OF STEC O157 VACCINES -- POPULATION EFFECTS OF VACCINATION -- MODELING THE VALUE OF VACCINATION -- CONCLUSION -- REFERENCES -- VACCINATION TO REDUCE FOODBORNE BACTERIAL PATHOGENS IN SWINE, WITH EMPHASIS ON SALMONELLA -- ABSTRACT -- INTRODUCTION -- SALMONELLA AS A ZOONOTIC PATHOGEN IN PIGS AND PORK -- PATHOGENESIS OF SALMONELLA INFECTIONS IN PIGS -- VACCINATING AGAINST SALMONELLA IN PIGS -- Activating Innate, Mucosal, Humoral and/or Cellular Immune Response? -- Using Live Attenuated or Inactivated Vaccines for Optimal Effects? -- Vaccinating Sows or Piglets? -- Interference of Vaccination with Salmonella Monitoring Programmes -- CONCLUSION -- REFERENCES -- PHYTOCHEMICALS AS A PREHARVEST PATHOGEN REDUCTION STRATEGY -- ABSTRACT -- INTRODUCTION -- CITRUS PULP AND CITRUS PEEL -- SAPONINS -- BETA-GLUCAN -- FLAVONOIDS -- CAROTENOIDS -- OTHER PHYTOCHEMICALS -- TOXIC IMPACT OF PHYTOCHEMICALS -- CONCLUSION -- REFERENCES -- ORGANIC ACIDS AND THEIR ROLE IN REDUCE FOODBORNE PATHOGENS IN FOOD ANIMALS -- ABSTRACT -- ORGANIC ACIDS MECHANISM OF ACTION -- The Anion Model -- Acid Shock Tolerance Response (ATR) -- ORGANIC ACIDS IN VITRO -- Effect of Organic Acids on Virulence Genes of Pathogenic Bacteria -- Organic Acid on Microflora and Foodborne Pathogens.

Multi-Hurdle Technique: The Synergy Between Organic Acids and Natural Compounds -- ORGANIC ACIDS IN VIVO -- Salmonella Literature Review -- Campylobacter Literature Review -- CONCLUSION -- REFERENCES -- STRESS EFFECTS ON PATHOGEN COLONIZATION OF FARM ANIMALS -- ABSTRACT -- INTRODUCTION -- STRESS IN FARM ANIMALS -- PATHOGEN COLONIZATION OF FARM ANIMALS -- HOW CAN STRESS AFFECT PATHOGENS IN THE GASTROINTESTINIAL TRACT OF FARM ANIMALS? -- EFFECT OF STRESS ON FOODBORNE PATHOGENS IN FARM ANIMALS -- CONCLUSION -- REFERENCES -- LESSER MEALWORMS ON POULTRY FARMS: A POTENTIAL ARENA FOR THE DISSEMINATION OF PATHOGENS AND ANTIMICROBIAL RESISTANCE -- ABSTRACT -- NATURAL HISTORY AND STRUCTURAL DAMAGE -- Life Cycle -- PREVALENCE IN POULTRY LITTER AND ENVIRONMENTAL REQUIREMENTS -- Litter Clean-out -- Temperature -- Distribution -- Bedding Type -- FLOCK HEALTH AND PATHOGEN DISSEMINATION -- FLOCK HEALTH AND ANTIBIOTIC RESISTANCE GENE DISSEMINATION -- Gastrointestinal (GIT) Reservoir -- Antimicrobial Use -- Environmental Factors Involed in Dissemination -- The Genetics of Dissemination -- Molecular Mechanisms -- Insect Reservoirs of Antimicrobial Resistance Vectors -- Inhibition of Plasmid Transfer -- ALPHITOBIUS DIAPERINUS AND OLFACTORY SECRETIONS -- ALPHITOBIUS DIAPERINUS AND CONTROL MEASURES -- Mechanical Barriers -- Diatomaceous Earth -- Boric Acid -- Chemical Insecticides -- Antifeedants -- Insect Growth Regulators -- Natural Enemies -- SUMMARY -- ACKNOWLEDGEMENT -- REFERENCES -- ABOUT THE EDITORS -- INDEX.