Half Title page -- Title page -- Copyright page -- Sponsors -- Officers and Organizing Committees -- Members of the Administrative Committee of the WAVD -- Preface -- Part 1: Allergy -- Chapter 1.1: Epidemiology of human atopic dermatitis - seven areas of notable progress and seven areas of notable ignorance -- Introduction -- Seven areas of notable progress -- Seven areas of notable ignorance -- Reflections -- References -- Chapter 1.2: The genomics revolution: will canine atopic dermatitis be predictable and preventable? -- Introduction -- Investigating AD-associated genotypes -- Genomic studies in canine AD -- Conclusions -- Glossary -- References -- Chapter 1.3: Serum anti-Staphylococcus pseudintermedius IgE and IgG antibodies in dogs with atopic dermatitis and nonatopic dogs -- Introduction -- Materials and methods -- Results -- Discussion -- Acknowledgements -- References -- Chapter 1.4: Characterization of canine filaggrin: gene structure and protein expression in dog skin -- Introduction -- Materials and methods -- Results -- Discussion -- Acknowledgements -- References -- Supporting Information -- Part 2: Immunology -- Chapter 2.1: Innate immune defense system of the skin -- Introduction -- Antimicrobial peptides -- Cathelicidins -- β-Defensins -- Dermcidin -- Psoriasin -- Antimicrobial peptide production in atopic dermatitis -- Conclusion -- References -- Chapter 2.2: Evaluation of canine antimicrobial peptides in infected and noninfected chronic atopic skin -- Introduction -- Material and methods -- Results -- Discussion -- Acknowledgements -- References -- Chapter 2.3: Interleukin-31: its role in canine pruritus and naturally occurring canine atopic dermatitis -- Introduction -- Materials and methods -- Results -- Discussion -- Acknowledgements -- References -- Supporting Information.

Chapter 2.4: Expression of thymic stromal lymphopoietin in canine atopic dermatitis -- Introduction -- Materials and methods -- Results -- Discussion -- References -- Part 3: Skin Biology -- Chapter 3.1: The stratum corneum: the rampart of the mammalian body -- Introduction -- Stratum corneum components crucial for barrier function -- Cutaneous manifestations associated with the alteration of SC components in humans and other mammalian species -- Implications and future perspectives for biological and clinical research -- References -- Chapter 3.2: Fixing the skin barrier: past, present and future - man and dog compared -- What is known in human medicine -- What is known in dogs -- Concluding remarks -- References -- Chapter 3.3: Autosomal recessive ichthyosis in golden retriever dogs: distribution and frequency of the PNPLA1 mutant allele in different populations -- Introduction -- Materials and methods -- Results -- Discussion -- Acknowledgements -- References -- Chapter 3.4: Epidermal structure created by canine hair follicle keratinocytes enriched with bulge cells in a three-dimensional skin equivalent model in vitro: implications for regenerative therapy of canine epidermis -- Introduction -- Materials and methods -- Results -- Discussion -- Acknowledgements -- References -- Chapter 3.5: Skin lipid profiling in normal and seborrhoeic shih tzu dogs -- Introduction -- Material and methods -- Results -- Discussion -- Acknowledgements -- References -- Part 4: Therapy -- Chapter 4.1: Stem cell therapy in veterinary dermatology -- Introduction -- Sources and types of stem cells -- Identification and characterization of the mesenchymal stem cell -- Mechanisms of action of the mesenchymal stem cell -- Engineered skin -- Mesenchymal stem cell therapy of chronic nonhealing wounds -- Mesenchymal stem cell therapy of immune-mediated skin diseases.

Mesenchymal stem cell therapy of scar tissue -- Mesenchymal stem cell therapy in alopecia -- Bulge stem cell markers in oncology -- US Food and Drug Administration (FDA) regulation of stem cell therapy in veterinary medicine -- Future perspectives of stem cell therapy in veterinary dermatology -- References -- Chapter 4.2: A systematic review of randomized controlled trials for prevention or treatment of atopic dermatitis in dogs: 2008-2011 update -- Introduction -- Objectives -- Methods -- Results -- Discussion -- Conclusions -- References -- Chapter 4.3: The effect of ketoconazole on whole blood and skin ciclosporin concentrations in dogs -- Introduction -- Materials and methods -- Results -- Discussion -- Acknowledgements -- References -- Chapter 4.4: In vitro antiseptic susceptibilities for Staphylococcus pseudintermedius isolated from canine superficial pyoderma in Japan -- Introduction -- Materials and methods -- Results -- Discussion -- References -- Supporting Information -- Chapter 4.5: Photodynamic therapy for pythiosis -- Introduction -- Material and methods -- Results -- Discussion -- References -- Part 5: Infectious Diseases -- Chapter 5.1: The canine and feline skin microbiome in health and disease -- Introduction -- Assessment of microbial populations -- The human skin -- The canine and feline skin bacterial microbiota: culture-dependent studies -- The canine and feline skin microbiomes: culture-independent studies -- Role of the skin microbiome in health and disease -- Manipulation of the skin microbiome -- Conclusion -- References -- Chapter 5.2: Ulcerated and nonulcerated nontuberculous cutaneous mycobacterial granulomas in cats and dogs -- Introduction -- Canine leproid granuloma (canine leprosy) -- Feline leprosy syndromes -- Treatment of canine leproid granuloma and feline leprosy syndrome.

Localized infections due to Mycobacterium ulcerans -- Zoonotic implications -- Acknowledgements -- References -- Supporting information -- Chapter 5.3: Prevalence of and risk factors for isolation of meticillin-resistant Staphylococcus spp. from dogs with pyoderma in northern California, USA -- Introduction -- Materials and methods -- Results -- Discussion -- Acknowledgements -- References -- Chapter 5.4: Usefulness of cefovecin disk-diffusion test for predicting mecA gene-containing strains of Staphylococcus pseudintermedius and clinical efficacy of cefovecin in dogs with superficial pyoderma -- Introduction -- Materials and methods -- Results -- Discussion -- Acknowledgements -- References -- Chapter 5.5: Small Demodex populations colonize most parts of the skin of healthy dogs -- Introduction -- Materials and methods -- Results -- Discussion -- Acknowledgements -- References -- Part 6: Oncology -- Chapter 6.1: Advances in the management of skin cancer -- Introduction -- Receptor tyrosine kinase inhibitors -- Retinoids -- Toll-like receptor agonists -- Histone deacetylase inhibitors -- BRAF inhibitors -- Xenogeneic DNA vaccine for canine melanoma -- Monoclonal antibodies -- Monoclonal antibodies in the treatment of skin cancer -- Identifying appropriate targets -- The hurdles to clinical advancement -- Conclusions -- References -- Chapter 6.2: Kinase dysfunction and kinase inhibitors -- Protein kinases and normal cell biology -- Resistance to therapy -- Summary -- References -- Chapter 6.3: The contribution of stem cells to epidermal and hair follicle tumours in the dog -- Introduction -- Materials and methods -- Results -- Discussion -- Acknowledgements -- References -- Supporting Information -- Chapter 6.4: Epithelial-to-mesenchymal transition: immunohistochemical investigation of related molecules in canine cutaneous epithelial tumours.

Introduction -- Materials and methods -- Results -- Discussion -- References -- Chapter 6.5: Canine inflamed nonepitheliotropic cutaneous T-cell lymphoma: a diagnostic conundrum -- Introduction -- Materials and methods -- Results -- Discussion -- Acknowledgements -- References -- Part 7: Equine Dermatology -- Chapter 7.1: Comparison of hair follicle histology between horses with pituitary pars intermedia dysfunction and excessive hair growth and normal aged horses -- Introduction -- Materials and methods -- Results -- Discussion -- Acknowledgements -- References -- Chapter 7.2: Equine sarcoidosis: clinical signs, diagnosis, treatment and outcome of 22 cases -- Introduction -- Materials and methods -- Results -- Discussion -- Acknowledgements -- References -- Part 8: Workshop Reports -- Chapter 8.1: Nonpruritic hair loss -- Canine recurrent flank alopecia (CRFA) (S. Vandenabeele) -- Alopecia in silver Labrador retrievers (V. Fadok and C. Vitale) -- Description and characterization of a hair coat disorder in schipperkes (E.R. May) -- Treatment of alopecia X with progesterone (L.A. Frank) -- References -- Chapter 8.2: Dietary management of skin disease: elimination diets and dietary approach to canine allergic disease -- References -- Chapter 8.3: Fun with lasers -- Light, tissue and magic: a peek behind the curtain (G.M. Peavy) -- New frontiers in structural and functional optical diagnostics (G.M. Peavy) -- Chapter 8.4: Allergen-specific immunotherapy -- Rush immunotherapy (A. Foust) -- Early experiences in sublingual immunotherapy (V. Fadok) -- How to utilize allergen cross-reactivity for formulation of immunotherapy (K. Lee) -- References -- Chapter 8.5: Pododermatitis: canine interdigital follicular cysts and feline plasma cell pododermatitis -- Interdigital cysts (D. Duclos) -- Medical therapy of interdigital furunculosis (J.C. Angus).

Feline plasma cell pododermatitis (B.E. Wildermuth).