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Analyzing Protein Dynamics Using Hydrogen Exchange Mass Spectrometry
Title:
Analyzing Protein Dynamics Using Hydrogen Exchange Mass Spectrometry
Author:
Hentze, Nikolai
Personal Author:
Publication Information:
Cambridge, MA MyJoVE Corp 2016
Physical Description:
online resource (697 seconds)
Series:
Chemistry
General Note:
Title from resource description page
Abstract:
Protein conformation and dynamics are key to understanding the relationship between protein structure and function. Hydrogen exchange coupled with high-resolution mass spectrometry is a versatile method to study the conformational dynamics of proteins as well as characterizing protein-ligand and protein-protein interactions, including contact interfaces and allosteric effects.
Reading Level:
For undergraduate, graduate, and professional students
Subject Term:
Electronic Access:
https://www.jove.com/t/50839