Building on a range of disciplines – from biology and anthropology to philosophy and linguistics – this book draws on the expertise of leading names in the study of organic, mental and cultural codes brought together by the emerging discipline of biosemiotics. The book’s 18 chapters present a range of experimental evidence which suggests that the genetic code was only the first in a long series of organic codes, and that it has been the appearance of new codes – organic, mental and cultural – that paved the way for the major transitions in the history of life. While the existence of many organic codes has been proposed since the 1980s, this volume represents the first multi-authored attempt to deal with the range of codes relevant to life, and to reveal the ubiquitous role of coding mechanisms in both organic and mental evolution. This creates the conditions for a synthesis of biology and linguistics that finally overcomes the old divide between nature and culture. The book will appeal to all those interested in the origins and evolution of life, including biologists (from molecular and cellular biologists to evolutionary and developmental biologists), ecologists, anthropologists, psychologists, philosophers of science, linguists, and researchers interested in the history of science, the origins of life, artificial life and intelligence, and information theory and communication technology. Marcello Barbieri is Professor of Embryology at the University of Ferrara, Italy, president of the Italian Association for Theoretical Biology, Editor-in-Chief of the Journal of Biosemiotics, and Co-Editor of the Springer book series in Biosemiotics.