Title page -- Preface -- Contents -- Introductory Overview -- Dissemination and Persistence are Pathogenic Events Common to All of the Major Human Spirochetal Infections -- Molecular Genetics of Spirochetes -- Transposon Mutagenesis of Infectious Borrelia burgdorferi B31: A Pilot Study -- The Isolation and Characterization of Isogenic Mutants in Infectious Borrelia burgdorferi -- Motility Gene Regulation and Chemotaxis in Borrelia burgdorferi -- Targeted and Random Mutagenesis in Leptospira biflexa: Application for the Functional Analysis of Iron Transporters -- Antibiotic Resistance in Borrelia burgdorferi: Applications for Genetic Manipulation and Implications for Evolution -- Development of Treponeme Genetic Systems -- Genomics and Diversity -- Comparative Genomics of Borrelia burgdorferi -- Treponema Genomics -- Comparative Analysis of Pathogenic Leptospira Genomes -- Leptospira interrogans: Genomics and "Immunomics" -- Genotypic Variation and Borrelia burgdorferi Pathogenesis -- Multilocus Sequence Analysis (MLSA) as an Alternative to Whole DNA/DNA Hybridization (WDDH) in Borrelia burgdorferi sensu lato Taxonomy -- Diversity and Variability of Protein-Encoding Genes of Borrelia burgdorferi sensu lato and Implications for Pathogenesis and Diagnosis of Lyme Borreliosis in Europe -- Are Borrelia recurrentis and Borrelia duttonii the Same Spirochaete? -- Genotyping of Borrelia burgdorferi sensu lato in Russia -- Ecological and Genetic Diversity Within the Leptospiraceae Family: Implications for Epidemiology -- Characterization of Borrelia burgdorferi sensu lato from Czech Patients and Ticks by Culture and PCR-Sequence Analysis -- Infection of Ixodid Ticks, Mosquitoes and Patients with Borrelia, Bartonella, Rickettsia, Anaplasma, Ehrlichia and Babesia in Western Siberia, Russia -- Gene Expression.

Genetic Studies of the Borrelia burgdorferi bmp Gene Family -- Porins of Borrelia -- Use of Green Fluorescent Protein Transcriptional Reporters to Study Differential Gene Expression by Borrelia burgdorferi -- Regulation of Expression of the Integrin Ligand P66 in Borrelia burgdorferi -- The Telomere Resolvase ResT and Evolution of the Borrelia Genomes -- Hairpin Telomeres of Linear Bacterial Chromosomes and Plasmids: How to Make Them -- Interactions of Spirochetes and Hosts -- Blood-Induced Transcriptional Changes in Borrelia burgdorferi -- Roles of Leptospiral Outer Membrane Proteins in Pathogenesis and Immunity -- Genetic Analysis of Attachment of Borrelia burgdorferi to Host Cells and Extracellular Matrix -- Borrelia burgdorferi and Ixodes scapularis: Exploring the Pathogen-Vector Interface -- The Lyme Disease Spirochete Erp Protein Family: Structure, Function and Regulation of Expression -- Lyme Disease Spirochetes Evade Innate Immunity by Acquisition of Complement Regulators, Factor H, and FHL-1 -- Outer Surface Lipoproteins of Borrelia burgdorferi: Role in Virulence, Persistence of the Pathogen, and in Protection Against Lyme Disease -- Localization of Lyme Disease and Relapsing Fever Spirochetes in Mammalian Hosts Infected with Different Borrelia Species, Strains, and Serotypes -- Author Index.