Cover image for Actin-Monomer-Binding Proteins
Actin-Monomer-Binding Proteins
Title:
Actin-Monomer-Binding Proteins
Author:
Lappalainen, Pekka. author.
ISBN:
9780387464077
Personal Author:
Physical Description:
XIV, 118 p. online resource.
Series:
Molecular Biology Intelligence Unit
Contents:
How Actin Assembly Is Modulated at Filament Barbed Ends in Motile Processes -- Proteins of the Actin Depolymerizing Factor/Cofilin Family -- Profilin, an Essential Control Element for Actin Polymerization -- Srv2/Cyclase-Associated Protein (CAP) -- Twinfilin Family of Actin Monomer-Binding Proteins -- Intracellular ?-Thymosins -- Multirepeat ?-Thymosins -- Wasp and WAVE Family Proteins -- The Verprolins as Regulators of Actin Dynamics -- A Common Binding Site for Actin-Binding Proteins on the Actin Surface.
Abstract:
The actin cytoskeleton plays a central role in many cellular processes including cell motility, cytokinesis, endocytosis and phagocytosis. The structure and dynamics of the actin cytoskeleton is regulated by a large number of proteins that interact with monomeric and/or filamentous actin. Actin monomer binding proteins provides a comprehensive view on actin monomer-binding proteins and the mechanisms by which they contribute to actin dynamics and various actin-dependent cellular processes. This new title contains chapters that describe the basic mechanisms of actin dynamics as well as the structural principles by which various actin-binding proteins interact with actin.
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