Micro-and Nanoelectromechanical Biosensors.
Title:
Micro-and Nanoelectromechanical Biosensors.
Author:
Nicu, Liviu.
ISBN:
9781118760987
Personal Author:
Edition:
1st ed.
Physical Description:
1 online resource (144 pages)
Series:
FOCUS Series
Contents:
Cover -- Title Page -- Contents -- Introduction -- CHAPTER 1. TRANSDUCTION TECHNIQUES FOR MINIATURIZED BIOSENSORS -- 1.1. Definition of bioMEMS -- 1.2. Transduction techniques -- 1.2.1. Optical transduction -- 1.2.2. Electro (chemical) transduction -- 1.2.3. Mechanical transduction -- 1.3. MEMS transducers -- 1.4. One specific application of MEMS biosensors: detection of pathogen agents -- 1.5. Bibliography -- CHAPTER 2. BIORECEPTORS AND GRAFTING METHODS -- 2.1. Types of bioreceptor -- 2.1.1. Catalytic receptors -- 2.1.2. Affinity receptors -- 2.1.3. Nucleic acid-based receptors -- 2.1.4. Molecularly imprinted polymers -- 2.2. Immobilization strategies -- 2.2.1. Adsorption and antifouling strategies -- 2.2.2. Entrapment methods -- 2.2.3. Covalent coupling -- 2.2.4. Other capture systems -- 2.2.5. Immobilization strategies: summary -- 2.3. Conclusion -- 2.4. Bibliography -- CHAPTER 3. PATTERNING TECHNIQUES FOR THE BIOFUNCTIONALIZATION OF MEMS -- 3.1. What is surface patterning? -- 3.2. Direct biopatterning in liquid phase -- 3.2.1. Ink delivery by non-contact methods -- 3.2.2. Ink delivery by contact methods -- 3.3. Replication of patterns -- 3.3.1. Photolithography -- 3.3.2. Light-induced patterning strategies -- 3.3.3. Microcontact printing -- 3.3.4. In-flux functionalization -- 3.4. Conclusions -- 3.5. Bibliography -- CHAPTER 4. FROM MEMS TO NEMS BIOSENSORS -- 4.1. Importance of downscaling -- 4.2. Challenges faced by NEMS for biosensing applications -- 4.2.1. Issues related to nanomechanical transducers -- 4.2.2. Issues related to the functionalization of NEMS -- 4.2.3. On the importance of packaging and sample preparation -- 4.3. Economic considerations -- 4.4. Bibliography -- CHAPTER 5. COMPARING PERFORMANCES OF BIOSENSORS: IMPOSSIBLE MISSION? -- 5.1. Bibliography -- INDEX.
Abstract:
Most books dedicated to the issues of bio-sensing are organized by the well-known scheme of a biosensor. In this book, the authors have deliberately decided to break away from the conventional way of treating biosensing research by uniquely addressing biomolecule immobilization methods on a solid surface, fluidics issues and biosensing-related transduction techniques, rather than focusing simply on the biosensor. The aim is to provide a contemporary snapshot of the biosensing landscape without neglecting the seminal references or products where needed, following the downscaling (from the micro- to the nanoscale) of biosensors and their respective best known applications. To conclude, a brief overview of the most popularized nanodevices applied to biology is given, before comparing biosensor criteria in terms of targeted applications.
Local Note:
Electronic reproduction. Ann Arbor, Michigan : ProQuest Ebook Central, 2017. Available via World Wide Web. Access may be limited to ProQuest Ebook Central affiliated libraries.
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