Predicting In Vivo Payloads Delivery using a Blood-brain Tumor-barrier in a Dish
Title:
Predicting In Vivo Payloads Delivery using a Blood-brain Tumor-barrier in a Dish
Author:
Le Joncour, Vadim
Personal Author:
Publication Information:
Cambridge, MA MyJoVE Corp 2016
Physical Description:
online resource (814 seconds)
Series:
Cancer Research
General Note:
Title from resource description page
Abstract:
Drug targeting to central nervous system tumors is a major challenge. Here we describe a protocol to produce an in vitro mimic of the blood-brain tumor-barrier using murine and/or human cells and discuss their relevance for the predictability of central nervous system tumor targeting in vivo.
Reading Level:
For undergraduate, graduate, and professional students
Subject Term:
Electronic Access:
https://www.jove.com/t/59384