Role of ACE, ACE2 and Neprilysin in the Kidney -- ACE Inhibition in Heart Failure and Ischaemic Heart Disease -- Proteases of the Renin-Angiotensin System in Human Acute Pancreatitis -- The Renin-Angiotensin System in Pancreatic Stellate Cells: Implications in the Development and Progression of Type 2 Diabetes Mellitus -- Renin-Angiotensin System Proteases and the Cardiometabolic Syndrome: Pathophysiological, Clinical and Therapeutic Implications -- The Role of the Renin-Angiotensin System in Hepatic Fibrosis -- The Renin-Angiotensin System in the Breast -- Role of Local Renin-Angiotensin System in the Carotid Body and in Diseases -- Bone Homeostasis: An Emerging Role for the Renin-Angiotensin System -- The Renin-Angiotensin System and its Inhibitors in Human Cancers -- The Skeletal Muscle RAS in Health and Disease -- Local Angiotensin Generation and AT2 Receptor Activation -- ADAMs as Mediators of Angiotensin II Actions.