Painful multi-symptom disorders : a systems perspective / C. Richard Chapman -- Neurotrophic factors and nociceptor sensitization / Michael P. Jankowski and H. Richard Koerber -- The role of visceral afferents in disease / Julie A. Christianson and Brian M. Davis -- Cancer pain : from the development of mouse models to human clinical trials / Juan Miguel Jimenez Andrade and Patrick Mantyh -- Therapeutic targeting of peripheral cannabinoid receptors in inflammatory and neuropathic pain states / Igor Spigelman -- Molecular strategies for therapeutic targeting of primary sensory neurons in chronic pain syndromes / Ichiro Nishimura ... [et al.] -- Transgenic mouse models for the tracing of "pain" pathways / Allan I. Basbaum and João M. Bráz -- Cytokines in pain / Veronica I. Shubayev, Kinshi Kato, and Robert R. Myers -- Glial modulation in pain states : translation into humans / Ryan J. Horvath, Edgar Alfonso Romero-Sandoval, and Joyce A. De Leo -- On the role of ATP-gated P2X receptors in acute, inflammatory, and neuropathic pain / Estelle Toulme ... [et al.] -- Myalgia and fatigue : translation from mouse sensory neurons to fibromyalgia and chronic fatigue syndromes / Alan R. Light, Charles J. Vierck, and Kathleen C. Light -- Reflex autonomic responses evoked by group III and IV muscle afferents / Jennifer L. McCord and Marc P. Kaufman -- Central pain as a thalamocortical dysrhythmia : a thalamic efference disconnection? / Kerry D. Walton and Rodolfo R. Llinás -- What can neuroimaging tell us about central pain? / D.S. Veldhuijzen ... [et al.] -- Human brain imaging studies of chronic pain : translational opportunities / A. Vania Apkarian -- Consideration of pharmacokinetic pharmacodynamic relationships in the discovery of new pain drugs / Garth T. Whiteside and Jeffrey D. Kennedy -- Large animal models for pain therapeutic development / Darrell A. Henze and Mark O. Urban -- Drug discovery and development for pain / Sandra R. Chaplan, William A. Eckert III, and Nicholas I. Carruthers.