Monitoring Cancer Cell Invasion and T-Cell Cytotoxicity in 3D Culture
Title:
Monitoring Cancer Cell Invasion and T-Cell Cytotoxicity in 3D Culture
Author:
Lin, Yuan-Na
Personal Author:
Publication Information:
Cambridge, MA MyJoVE Corp 2016
Physical Description:
online resource (464 seconds)
Series:
Cancer Research
General Note:
Title from resource description page
Abstract:
The presented approach simultaneously evaluates cancer cell invasion in 3D spheroid assays and T-cell cytotoxicity. Spheroids are generated in a scaffold-free agarose multi-microwell cast. Co-culture and embedding in type I collagen matrix are performed within the same device which allows to monitor cancer cell invasion and T-cell mediated cytotoxicity.
Reading Level:
For undergraduate, graduate, and professional students
Subject Term:
Electronic Access:
https://www.jove.com/t/61392