A Data Integration Workflow to Identify Drug Combinations Targeting Synthetic Lethal Interactions
Title:
A Data Integration Workflow to Identify Drug Combinations Targeting Synthetic Lethal Interactions
Author:
Marhold, Maximilian
Personal Author:
Publication Information:
Cambridge, MA MyJoVE Corp 2016
Physical Description:
online resource (460 seconds)
Series:
Cancer Research
General Note:
Title from resource description page
Abstract:
Large genetic screens in model organisms have led to the identification of negative genetic interactions. Here, we describe a data integration workflow using data from genetic screens in model organisms to delineate drug combinations targeting synthetic lethal interactions in cancer.
Reading Level:
For undergraduate, graduate, and professional students
Subject Term:
Electronic Access:
https://www.jove.com/t/60328