Cover image for Enzyme Technologies : Metagenomics, Evolution, Biocatalysis and Biosynthesis.
Enzyme Technologies : Metagenomics, Evolution, Biocatalysis and Biosynthesis.
Title:
Enzyme Technologies : Metagenomics, Evolution, Biocatalysis and Biosynthesis.
Author:
Yeh, Wu-Kuang.
ISBN:
9780470627297
Personal Author:
Edition:
1st ed.
Physical Description:
1 online resource (390 pages)
Series:
Chemical Biology of Enzymes for Biotechnology and Pharmaceutical Applications ; v.3

Chemical Biology of Enzymes for Biotechnology and Pharmaceutical Applications
Contents:
ENZYME TECHNOLOGIES -- CONTENTS -- Contributors -- Preface -- PART A NEW APPROACHES TO FINDING AND MODIFYING ENZYMES -- 1 Functional Metagenomics as a Technique for the Discovery of Novel Enzymes and Natural Products -- 2 Directed Enzyme and Pathway Evolution -- 3 Combining Natural Biodiversity and Molecular-Directed Evolution to Develop New Industrial Biocatalysts and Drugs -- 4 Principles of Enzyme Optimization for the Rapid Creation of Industrial Biocatalysts -- PART B BIOCATALYTIC APPLICATIONS -- 5 Enzyme Catalysis in the Synthesis of Active Pharmaceutical Ingredients -- 6 Enzymatic Processes for the Production of Pharmaceutical Intermediates -- 7 Novel Developments Employing Redox Enzymes: Old Enzymes in New Clothes -- PART C BIOSYNTHETIC APPLICATIONS -- 8 Drug Discovery and Development by Combinatorial Biosynthesis -- 9 Reprogramming Daptomycin and A54145 Biosynthesis to Produce Novel Lipopeptide Antibiotics -- 10 Pathway and Enzyme Engineering and Applications for Glycodiversification -- Index.
Abstract:
Wu-Kuang Yeh, PhD, is Executive Consultant and was director of research and principal investigator at PreClinOmics, Inc., from 2004-2010. He was a principal research scientist at Eli Lilly and Company from 1982-2004. He is the author or coauthor of over 115 abstracts and publications, coeditor of one book, and the holder of six U.S. patents. Hsiu-Chiung Yang, PhD, is a Research Advisor at Eli Lilly and Company. She was a principal research scientist at Eli Lilly and Company from 1998-2007 and is the author or coauthor of over forty abstracts and publications, as well as co-inventor of one patent. James R. Mccarthy, PhD, is the author, coauthor, or coeditor of over 125 scientific publications and holder of over forty U.S. patents. He is on the editorial advisory board of the Journal of Medicinal Chemistry and is a past chair of the division of Medicinal Chemistry of the American Chemical Society. He also serves as a Senior Scientific Advisor for the Huntington Disease Research Foundation.
Local Note:
Electronic reproduction. Ann Arbor, Michigan : ProQuest Ebook Central, 2017. Available via World Wide Web. Access may be limited to ProQuest Ebook Central affiliated libraries.
Electronic Access:
Click to View
Holds: Copies: