FrontMatter -- Reviewers -- Preface -- Acknowledgments -- Contents -- Abbreviations and Acronyms -- Summary -- 1 Introduction -- 2 Evaluating the Current State of Patient Safety and Health IT -- 3 Examination of the Current State of the Art in System Safety and Its Relationship to the Safety of Health IT-Assisted Care -- 4 Opportunities to Build a Safer System for Health IT -- 5 Patients' and Families' Use of Health IT: Concerns About Safety -- 6 A Shared Responsibility for Improving Health IT Safety -- 7 Future Research for Care Transformation -- Appendix A: Glossary -- Appendix B: Literature Review Methods -- Appendix C: Abstract of "Roadmap for Provision of Safer Healthcare Information Systems: Preventing e-Iatrogenesis" -- Appendix D: Abstract of "The Impact of Regulation on Innovation in the United States: A Cross-Industry Literature Review" -- Appendix E: Dissenting Statement: Health IT Is a Class III Medical Device -- Appendix F: Committee Member and Staff Biographies.