Reviewers -- Foreword -- Preface -- Acknowledgments -- Contents -- Boxes, Figures, and Tables -- Summary -- 1 Introduction -- 2 What Is Comparative Effectiveness Research? -- 3 Obtaining Input to Identify National Priorities for Comparative Effectiveness Research -- 4 The Criteria and Process for Setting Priorities -- 5 Priorities for Study -- 6 Essential Priorities for a Robust CER Enterprise -- Appendix A: Public Meeting Agenda-March 20, 2009 -- Appendix B: Stakeholder Questionnaire -- Appendix C: Data Tables: Burden of Disease and Variation of Care -- Appendix D: Cardiovascular and Peripheral Vascular Cover Sheet -- Appendix E: Definitions of Medical Terminology in CER Priority List -- Appendix F: Committee Biographies.