Chronic Myeloid Leukemia — A Brief History -- Bcr-Abl and Signal Transduction -- Chronic Myeloid Leukemia: Biology of Advanced Phase -- Clinical Features of CML -- Signal Transduction Inhibitors in Chronic Myeloid Leukemia -- Treatment with Tyrosine Kinase Inhibitors -- Allogeneic Transplantation for CML -- Autografting in Chronic Myeloid Leukemia -- Monitoring Disease Response -- New Therapies for Chronic Myeloid Leukemia -- Immune Therapy of Chronic Myelogenous Leukemia -- Therapeutic Strategies and Concepts of Cure in CML -- BCR-ABL-Negative Chronic Myeloid Leukemia -- Hypereosinophilic Syndrome -- Chronic Idiopathic Myelofibrosis -- Polycythemia Vera — Clinical Aspects -- Polycythemia Vera and Other Polycythemic Disorders — Biological Aspects -- Essential Thrombocythemia.