Yeast As a Chassis for Developing Functional Assays to Study Human P53
Title:
Yeast As a Chassis for Developing Functional Assays to Study Human P53
Author:
Monti, Paola
Personal Author:
Publication Information:
Cambridge, MA MyJoVE Corp 2016
Physical Description:
online resource (897 seconds)
Series:
Cancer Research
General Note:
Title from resource description page
Abstract:
Presented here are four protocols to construct and exploit yeast Saccharomyces cerevisiae reporter strains to study human P53 transactivation potential, impacts of its various cancer-associated mutations, co-expressed interacting proteins, and the effects of specific small molecules.
Reading Level:
For undergraduate, graduate, and professional students
Subject Term:
Electronic Access:
https://www.jove.com/t/59071