Contents -- Contributors -- PART I: INTRODUCTION TO BASIC NEUROSCIENCE -- 1. Overview of Brain Development -- 2. Neurochemical Systems in the Central Nervous System -- 3. Using Basic Electrophysiology to Understand the Neurobiology of Mental Illness -- 4. Principles of Signal Transduction -- 5. Mechanisms of Neural Plasticity -- 6. Principles of Molecular Biology -- 7. Functional Genomics and Models of Mental Illness -- PART II: METHODS OF CLINICAL NEUROBIOLOGICAL RESEARCH -- 8. Contributions of Epidemiology to the Neurobiology of Mental Illness -- 9. Basic Methods for Clinical Molecular Genetics of Psychiatric Illness -- 10. Methods of Affective Clinical Psychophysiology -- 11. Clinical Neurochemistry -- 12. Clinical Neuroendocrinology -- 13. Neuroimmunology -- 14. Cognitive Neuroscience: Bridging Thinking and Feeling to the Brain, and Its Implications for Psychiatry -- 15. Neuroimaging Methodologies: Utilizing Radiotracers or Nuclear Magnetic Resonance -- 16. Methods of Postmortem Investigation of Human Brain -- 17. Drug Discovery and Development Methods for Mental Illness -- PART III: PSYCHOSES -- 18. Diagnostic Classification of the Psychoses: Historical Context and Implications for Neurobiology -- 19. Molecular Genetics of Schizophrenia -- 20. Animal Models of the Psychoses -- 21. Pharmacological Models of Psychoses -- 22. The Neurobiology of Schizophrenia -- 23. Functional Brain Imaging Studies in Schizophrenia -- 24. Psychophysiological and Information Procesing Approaches to Schizophrenia -- 25. Principles of the Pharmacotherapy of Schizophrenia -- PART IV: MOOD DISORDERS -- 26. Diagnostic Classification of Mood Disorders: Historical Context and Implications for Neurobiology -- 27. Linkage and Association Studies of Bipolar Disorders -- 28. Animal Models of Mood Disorders -- 29. The Cellular Neurobiology of Bipolar Disorder.

30. The Neurochemistry of Depressive Disorders: Preclinical Studies -- 31. The Neurochemistry of Depressive Disorders: Clinical Studies -- 32. Neuroimaging Studies of Mood Disorders -- 33. Principles of the Pharmacotherapy of Depression -- 34. Abnormalities of Brain Structure and Function in Mood Disorders Based Upon Postmortem Investigations -- PART V: ANXIETY DISORDERS -- 35. Diagnostic Classification of Anxiety Disorders: DSM-V and Beyond -- 36. Molecular Genetics of Anxiety -- 37. Animal Models of Anxiety Disorders -- 38. Structural and Functional Plasticity in the Hippocampal Formation: Stress, Adaptation, and Disease -- 39. Functional Neuroanatomy of Anxiety and Fear -- 40. The Neurobiology of Anxiety Disorders -- 41. The Neurobiology and Treatment of Obsessive-Compulsive Disorder -- 42. Neuroimaging Studies of Anxiety Disorders -- 43. Principles of Pharmacotherapy for the Anxiety Disorders -- PART VI: SUBSTANCE ABUSE DISORDERS -- 44. Animal Models of Addiction -- 45. Cellular and Molecular Mechanisms of Drug Addiction -- 46. Genetic Epidemiology of Substance Use Disorders -- 47. Effects of Drugs of Abuse on Brain Development -- 48. Neuroimaging in Substance Abuse Research -- 49. Principles of the Pharmacotherpy of Substance Abuse Disorders -- PART VII: DEMENTIA -- 50. Diagnostic Classifications: Relationship to the Neurobiology of Dementia -- 51. The Molecular Biology of Alzheimer's Disease -- 52. Pharmacological and Transgenic Animal Models of Alzheimer's Disease -- 53. Functional Neuroanatomy of Learning and Memory -- 54. Neurochemical Systems Involved in Learning and Memory -- 55. Neuropathological and Neuroimaging Studies of the Hippocampus in Normal Aging and in Alzheimer's Disease -- 56. Abnormalities in Brain Structure on Postmortem Analysis of Dementia -- 57. Functional Brain Imaging Studies in Dementia.

58. Principles of the Pharmacotherapy of Dementia -- 59. Cognitive Impairment in Demyelinating Disease -- 60. Dementia with Lewy Bodies -- 61. Dementia in Parkinson's Disease -- PART VIII: PSYCHIATRIC DISORDERS OF CHILDHOOD ONSET -- 62. Developmental Neurobiology and the Childhood Onset of Psychiatric Disorders -- 63. Molecular Genetics of Childhood- and Adolescent-Onset Psychiatric Disorders -- 64. Neurobiology of Mental Retardation -- 65. The Neurobiology of Autism and the Pervasive Developmental Disorders -- 66. Tourette's Syndrome and Tic-Related Disorders in Children -- 67. Neurobiology of Attention Deficit Hyperactivity Disorder -- 68. The Neurobiology of Childhood Psychotic Disorders -- 69. Neurobiology of Early-Onset Mood Disorders -- 70. Childhood Anxiety Disorders: A Cognitive Neurobiological Perspective -- PART IX: SPECIAL TOPIC AREAS -- 71. Neuropsychiatry: The Border Between Neurology and Psychiatry -- 72. The Neurobiology of Personality and Personality Disorders -- 73. The Neurobiology of Aggression -- 74. Sexual Dysfunction and Pharmacological Treatments: Biological Interactions -- 75. The Neurobiology of Social Attachment -- 76. The Neurobiology of Eating Disorders -- 77. The Neurobiology of Menstrual Cycle-Related Mood Disorders -- 78. The Neurobiology of Circadian Rhythms -- 79. The Neurobiology of Sleep in Relation to Mental Illness -- 80. Depression, Cardiovascular Disease, and Cerebrovascular Disease: Implications for Pathophysiology and Treatment -- Index -- A -- B -- C -- D -- E -- F -- G -- H -- I -- J -- K -- L -- M -- N -- O -- P -- Q -- R -- S -- T -- U -- V -- W -- X -- Y -- Z.