Contents -- 1. Introduction -- 1.1 Introduction by the Director-General -- 1.2 Scope and aims -- 2. Global burden of disease -- 2.1 The Global Burden of Disease Study -- 2.1.1 Summary measures of population health -- 2.1.2 Health states -- 2.2 Estimating the global burden of musculoskeletal conditions -- 2.3 Methodology of estimating the burden of disease -- 3. Incidence and prevalence of musculoskeletal conditions -- 3.1 Introduction -- 3.1.1 Potential further sources of data -- 3.1.2 Recommendations for making estimates of incidence and prevalence of musculoskeletal conditions -- 3.2 Rheumatoid arthritis -- 3.2.1 Definition -- 3.2.2 Incidence -- 3.2.3 Prevalence -- 3.2.4 Potential sources of further data -- 3.2.5 Recommendations for making estimates of incidence and prevalence rates of the global burden -- 3.3 Osteoarthritis -- 3.3.1 Definition -- 3.3.2 Incidence -- 3.3.3 Prevalence -- 3.3.4 Potential sources of further data -- 3.3.5 Recommendations for making estimates of incidence and prevalence rates of the global burden -- 3.4 Osteoporosis -- 3.4.1 Definition -- 3.4.2 Incidence -- 3.4.3 Prevalence -- 3.4.4 Potential sources of further data -- 3.4.5 Recommendations for making estimates of incidence and prevalence of the global burden -- 3.5 Spinal disorders -- 3.5.1 Definition -- 3.5.2 Incidence -- 3.5.3 Prevalence -- 3.5.4 Potential sources of further data -- 3.5.5 Recommendations for making estimates of incidence and prevalence rates of the global burden -- 3.6 Severe limb trauma -- 3.6.1 Definition -- 3.6.2 Incidence -- 3.6.3 Prevalence -- 3.6.4 Potential sources of further data -- 3.6.5 Recommendations for making estimates of incidence and prevalence rates of the global burden -- 4. Severity and course of the conditions -- 4.1 Introduction -- 4.2 Rheumatoid arthritis -- 4.2.1 Model of the condition.

4.2.2 How has loss of health been described and quantified? -- 4.2.3 What is the role of geographical and socioeconomic factors? -- 4.3 Osteoarthritis -- 4.3.1 Model of the condition -- 4.3.2 How has loss of health been described and quantified? -- 4.3.3 What is the role of geographical and socioeconomic factors? -- 4.4 Osteoporosis -- 4.4.1 Model of the condition -- 4.4.1 How has loss of health been described and quantified? -- 4.4.3 What is the role of geographical and socioeconomic factors? -- 4.5 Spinal disorders -- 4.5.1 Model of the conditions -- 4.5.2 How has loss of health been described and quantified? -- 4.5.3 What is the role of geographical and socioeconomic factors? -- 4.5.4 Spinal pain and disability -- 4.6 Severe limb trauma -- 4.6.1 Model of the conditions -- 4.6.2 How has loss of health been described and quantified? -- 4.6.3 Role of geographical and socioeconomic factors -- 5. Health and economic indicators -- 5.1 The need for health indicators -- 5.2 What should be measured by indicators for musculoskeletal conditions? -- 5.2.1 General indicators -- 5.2.2 Risk factors -- 5.2.3 Specific interventions and treatments -- 5.2.4 Consequences of musculoskeletal conditions for the individual and society -- 5.2.5 Choice of indicators -- 5.3 Economic indicators -- 5.4 Summary -- 6. Measuring the health impact and economic burden of musculoskeletal conditions on the population -- 6.1 Introduction -- 6.2 Rheumatoid arthritis -- 6.2.1 Health indicators -- 6.2.2 Economic indicators -- 6.3 Osteoarthritis -- 6.3.1 Health indicators -- 6.3.2 Economic indicators -- 6.4 Osteoporosis -- 6.4.1 Health indicators -- 6.4.2 Economic indicators -- 6.5 Spinal disorders -- 6.5.1 Health indicators -- 6.5.2 Economic indicators -- 6.6 Severe limb trauma -- 6.6.1 Health indicators -- 6.6.2 Economic indicators.

7. Describing health status and the consequences of illness or injury for the individual -- 7.1 Introduction -- 7.1.1 Uses of data collected -- 7.1.2 Multidimensional health concept -- 7.1.3 Limitations of currently available measures -- 7.1.4 Boundary between health and well-being -- 7.1.5 Need for a common language and profile to describe health -- 7.1.6 Description versus valuation of health -- 7.1.7 Next steps -- 7.2 Multidimensional approach to measuring health status for musculoskeletal conditions -- 7.3 Rheumatoid arthritis -- 7.3.1 Health domains -- 7.3.2 Possible health states -- 7.3.3 Suggested instruments for measuring selected health domains -- 7.4 Osteoarthritis -- 7.4.1 Health domains -- 7.4.2 Possible health states -- 7.4.3 Suggested instruments for measuring selected health domains -- 7.5 Osteoporosis -- 7.5.1 Health domains -- 7.5.2 Possible health states -- 7.5.3 Suggested instruments for measuring selected health domains -- 7.5.4 Issues relating to children -- 7.6 Spinal disorders -- 7.6.1 Health domains -- 7.6.2 Possible health states -- 7.6.3 Suggested instruments for measuring selected health domains -- 7.7 Severe limb trauma -- 7.7.1 Health domains -- 7.7.2 Possible health states -- 7.7.3 Suggested instruments for measuring selected health domains -- 8. Inventory of published assessment instruments for musculoskeletal conditions -- 8.1 Introduction -- 8.2 Data collected -- 8.2.1 Instrument name -- 8.2.2 Bibliographic citation -- 8.2.3 Instruments designed for or used with various populations -- 8.2.4 Disease conditions -- 8.2.5 Reliability data -- 8.2.6 Validity data -- 8.2.7 Type of indicator -- 8.2.8 Areas measured -- 8.2.9 Administration -- 8.2.10 Time to complete -- 8.2.11 Language -- 8.2.12 Copy available -- 8.3 Search methodology -- 8.3.1 Experts in musculoskeletal conditions -- 8.3.2 Existing databases.

8.3.3 Review text -- 8.4 Selected instrument listings -- 9. Conclusions and recommendations -- 9.1 Incidence and prevalence -- 9.2 Severity and course of the condition -- 9.2.1 Rheumatoid arthritis -- 9.2.2 Osteoarthritis -- 9.2.3 Osteoporosis -- 9.2.4 Spinal disorders -- 9.2.5 Severe limb trauma -- 9.3 Health and economic indicators -- 9.4 Measuring health impact and economic burden at the population level -- 9.5 Describing health status as a consequence of illness or injury: impact on the individual -- 9.6 Recommendations of the Scientific Group -- Acknowledgements -- References -- Annex: Estimates of incidence or prevalence of key musculoskeletal disorders considered for each WHO region.