Cover image for Acute Promyelocytic Leukemia Molecular Genetics, Mouse Models and Targeted Therapy
Acute Promyelocytic Leukemia Molecular Genetics, Mouse Models and Targeted Therapy
Title:
Acute Promyelocytic Leukemia Molecular Genetics, Mouse Models and Targeted Therapy
Author:
Pandolfi, Pier Paolo. editor.
ISBN:
9783540345947
Physical Description:
VIII, 274 p. 16 illus., 9 illus. in color. online resource.
Series:
Current Topics in Microbiology and Immunology, 313
Contents:
APL as a Paradigm in Biomedical Research: A Journey Toward the Cure -- Mouse Models of Acute Promyelocytic Leukemia -- The PLZF Gene of t(11;17)-Associated APL -- SUMO, the Three Rs and Cancer -- Emerging Role for MicroRNAs in Acute Promyelocytic Leukemia -- The Theory of APL Revisited -- Treatment of Acute Promyelocytic Leukemia by Retinoids -- Arsenic Trioxide and Acute Promyelocytic Leukemia: Clinical and Biological -- Front Line Clinical Trials and Minimal Residual Disease Monitoring in Acute Promyelocytic Leukemia -- Histone Deacetylase Inhibitors in APL and Beyond -- Monoclonal Antibody Therapy of APL -- Targeting APL Fusion Proteins by Peptide Interference -- The Design of Selective and Non-selective Combination Therapy for Acute Promyelocytic Leukemia.
Abstract:
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