NF-κB-Related Genetic Diseases
Title:
NF-κB-Related Genetic Diseases
Author:
Courtois, Gilles. author.
ISBN:
9783319258508
Personal Author:
Edition:
1st ed. 2016.
Physical Description:
XII, 70 p. 17 illus. online resource.
Series:
SpringerBriefs in Biochemistry and Molecular Biology,
Contents:
1) The NF-kB signaling pathways: players and Functions -- 2) Genetic Diseases Affecting the Canonical Pathway of NF-kB Activation -- 3) Genetic Diseases Affecting hte Non-Camonical Pathway of NF-kB Activation -- 4) Genetic Diseases Affecting Ubiquitination Processes in NF-kB Signaling -- 5)Lessons Learned from Studying NF-kB Related Genetic Diseases.
Abstract:
This book presents the diverse clinical, cellular and molecular manifestations of NF-KB-related genetic diseases. It shows that studying patient-related pathologies affecting the components of the NF-KB signaling pathway offers the opportunity to understand the various functions of NF-KB in humans, complementing studies performed with mouse models. In addition, people treating those patients acquire a deeper understanding of the molecular basis of the pathophysiological processes.
Subject Term:
Added Corporate Author:
Electronic Access:
https://doi.org/10.1007/978-3-319-25850-8