Contents -- Contributors -- Preface -- 1 Themes in Bacterial Pathogenic Mechanisms -- Basic Steps in Pathogenesis Provide a Sound Foundation -- Refining Concepts of Virulence -- Critical Host-Bacteria Communication -- Promise of Genomics -- Evolution of Pathogens-Insights into the Road Ahead -- 2 Evolution of Bacterial Virulence -- Population Structures and Genome Plasticity: Sex in Bacteria -- Pathogenicity Islands: Not a Place for Fun -- Illustrations of Virulence Evolution -- Conclusion -- 3 Streptococcus -- Streptococcus agalactiae -- Streptococcus dysgalactiae -- Streptococcus equi -- Streptococcus zooepidemicus -- Streptococcus canis -- Streptococcus suis -- Streptococcus porcinus -- Streptococcus uberis -- Streptococcus pneumoniae -- Conclusions -- 4 Staphylococcus -- Characteristics of the Organism -- Pathogenic Staphylococcus Species -- Sources of the Bacterium -- Bacterial Virulence Factors -- Pathogenesis -- Types of Disease and Pathologic Changes -- Interactions Between the Bacterium and Host Defenses -- Immunity and Its Impact on Pathogenesis -- Conclusions: New Developments -- 5 Bacillus anthracis -- Epidemiology -- Bacteriology -- Pathogenesis -- Therapeutics -- Immunity and Control -- 6 Mycobacterium -- Virulence -- Host Response -- Granulomatous Lesion Development -- 7 Corynebacterium and Arcanobacterium -- Corynebacterium -- Corynebacterium bovis -- Corynebacterium kutscheri -- Corynebacterium pseudotuberculosis -- Corynebacterium renale, C. pilosum and C. cystitidis -- Corynebacterium ulcerans -- Arcanobacterium -- Arcanobacterium pyogenes -- Conclusions -- 8 Rhodococcus -- Characteristics and Sources of the Organism -- Bacterial Virulence Factors -- Pathogenesis -- Gaps in Knowledge and Anticipated Developments -- 9 Listeria -- Characteristics of the Bacterium -- Sources of the Bacterium -- Bacterial Virulence Factors.

Pathogenesis -- Host-Pathogen Interactions in Listeriosis -- Conclusions -- 10 Erysipelothrix rhusiopathiae -- Bacterial Virulence Factors -- Diseases -- Pathogenesis -- Acquired Immunity -- Conclusions -- 11 Neurotoxigenic Clostridia -- Botulism -- Characteristics of Clostridium botulinum -- Pathogenesis of Botulism -- Tetanus -- Pathogenesis of Tetanus -- Nature and Action of Botulinum and Tetanus Toxins -- Immunity to Botulism and Tetanus -- Conclusion -- 12 Histotoxic Clostridia -- Virulence Factors and Pathogenesis -- Conclusion -- 13 Enteric Clostridia -- Clostridium perfringens -- Clostridium septicum -- Clostridium difficile -- Clostridium spiroforme -- Conclusion -- 14 Salmonella -- Classification and Nomenclature -- Biochemical Characteristics and Bacterial Isolation -- Host Specificity -- Diseases Caused by Salmonella -- Virulence Factors -- Pathogenesis -- Immunity -- Antibiotic Resistance and Virulence -- Concluding Remarks -- 15 E. coli Shigella -- Disease -- Shigellosis in Animals -- Virulence Factors of E. coli Shigella -- Plasmids -- Pathogenesis of Shigellosis -- Immunity -- Toxins -- Concluding Remarks -- 16 Escherichia coli -- Types of E. coli Implicated in Disease -- Enterotoxigenic E. coli (ETEC) -- Pathogenesis -- Shiga Toxin-Producing Escherichia coli(STEC) -- Enteropathogenic E. coli (EPEC) -- Pathogenesis -- Extraintestinal E. coli (ExPEC) -- Immunity -- Concluding Remarks -- 17 Actinobacillus -- Actinobacillus pleuropneumoniae -- Actinobacillus suis -- Actinobacillus equuli -- Actinobacillus lignieresii -- Conclusions and Future Prospects -- 18 Haemophilus -- Characteristics -- Habitat and Transmission -- Haemophilus somnus -- Haemophilus parasuis -- Haemophilus paragallinarum -- Conclusions -- 19 Bordetella -- Characteristics of the Organism -- Sources of the Bacterium -- Bacterial Virulence Factors -- Pathogenesis.

Immunity -- Conclusion -- 20 Pasteurella and Mannheimia -- Pasteurella -- Diseases/Economic Impact -- Taxonomy, Nomenclature, and Typing -- Sources of the Bacteria -- Bacterial Virulence Factors -- Pathogenesis and Pathology -- Immunity -- Conclusions -- Mannheimia -- Characteristics of the Organism -- Sources of the Bacterium -- Bacterial Virulence Factors -- Pathogenesis -- Interactions Between the Bacterium and Host Defenses -- Immunity -- Conclusion -- 21 Yersinia -- Classification of Yersinia Species -- Sources of Yersinia Species -- Virulence Factors -- Pathogenesis -- Immunity -- Future Directions -- 22 Brucella -- Virulence -- Disease -- Brucella abortus -- Brucella melitensis -- Brucella ovis -- Brucella suis -- Brucella canis -- Host Response -- Disease Control -- 23 Pseudomonas -- Diseases -- Virulence Factors of P. aeruginosa -- Antibiotic Resistance -- "Genome-Mining" for Essential Genes -- Pathogenesis -- Vaccines -- Conclusions and Future Prospects -- 24 Moraxella -- Characteristics of the Organism -- Characteristics of M. bovis -- Infectious Bovine Keratoconjunctivitis (IBK) or Pinkeye -- 25 Campylobacter and Helicobacter -- Campylobacter -- Campylobacter fetus -- Campylobacter jejuni and C. coli -- Campylobacter upsaliensis, C. hyointestinalis, and C. mucosalis -- Helicobacter -- Helicobacter hepaticus and H. bilis -- Helicobacter pylori -- 26 Lawsonia intracellularis -- Characteristics of L. intracellularis -- Sources of L. intracellularis -- Virulence Factors -- Pathogenesis -- Conclusion -- 27 Gram-Negative Anaerobes -- General Bacterial Virulence Factors -- Bacteroides -- Fusobacterium -- Prevotella and Porphyromonas -- Dichelobacter -- Treponema -- Brachyspira -- Overall Conclusions and Future Work -- 28 Leptospira -- Introduction and Historical Perspectives -- Characteristics of the Organism -- Sources of the Bacterium.

Bacterial Virulence Factors -- Pathogenesis -- Conclusions -- 29 Mycoplasma -- Characteristics of the Organism -- Sources of the Bacterium -- Bacterial Virulence Factors -- Pathogenesis -- Interactions -- Protective Immunity -- Conclusions and Future Directions -- 30 Chlamydia -- Classification -- Hosts and Kinds of Disease -- Life Cycle -- Host Response -- Diseases -- Pathogenesis -- 31 Rickettsiales -- Characteristics of Rickettsial Organisms -- Animal Rickettsial Pathogens-Family Anaplasmataceae -- Animal Rickettsial Pathogens-Family Rickettsiaceae -- Conclusion -- Index.